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中国偏头痛治疗药物应用现状满意度调查:中药与西药治疗偏头痛急性发作的疗效比较如何?

A satisfaction survey of current medicines used for migraine therapy in China: is Chinese patent medicine effective compared with Western medicine for the acute treatment of migraine?

机构信息

Department of Neurology, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China; Affiliated Liuzhou Hospital of Southern Medical University, Guangxi, China.

出版信息

Pain Med. 2014 Feb;15(2):320-8. doi: 10.1111/pme.12277. Epub 2013 Nov 8.

DOI:10.1111/pme.12277
PMID:24524844
Abstract

OBJECTIVE

To investigate the patient satisfaction with medications commonly used for migraine therapy in patients seen in headache clinic in China with emphasis on the evaluation of Chinese patent medicine (CPM) in relieving acute migraine attack.

METHODS

Patients admitted at headache clinics in the neurological departments of four hospitals during April to October 2011 were enrolled in the investigation. The questionnaire was designed based on the validation of a diagnostic questionnaire for a population-based survey in China in 2009.

RESULTS

Among 219 eligible patients, 58% had used CPM at the acute attack of migraine while the guideline-recommended treatments were seldom used. However, patients using CPMs were less satisfied than those using Western Medicines (WMs) in either single medication groups or mixed medication groups (P < 0.05).

CONCLUSION

Fifty-eight percent of the eligible respondents in Guangdong and Guangxi Province had used CPM at the acute attack of migraine, but based on our data, the effect of CPM on treating migraine attack was poor with low satisfaction compared with WMs. However, many factors may bias or explain our findings. This suggests the need for accelerated research in understanding patient choice, treatment availability, and use of medications.

摘要

目的

调查在中国头痛诊所就诊的偏头痛患者对常用药物治疗的满意度,重点评估中药(CPM)在缓解急性偏头痛发作方面的效果。

方法

2011 年 4 月至 10 月,在 4 家医院的神经内科头痛诊所招募入组患者。调查问卷基于中国 2009 年一项基于人群的调查的诊断问卷进行了验证。

结果

在 219 名符合条件的患者中,58%的患者在偏头痛急性发作时使用了 CPM,而指南推荐的治疗方法则很少使用。然而,在单一药物组或混合药物组中,使用 CPM 的患者的满意度均低于使用西药(WM)的患者(P<0.05)。

结论

在广东和广西的合格受访者中,有 58%的人在偏头痛急性发作时使用了 CPM,但根据我们的数据,CPM 治疗偏头痛发作的效果较差,满意度低于 WM。然而,许多因素可能会使我们的研究结果产生偏差或做出错误解释。这表明需要加快研究以了解患者的选择、治疗方法的可及性和药物的使用情况。

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