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自我保护措施在控制人群传染病的最佳干预措施中的影响。

The impact of self-protective measures in the optimal interventions for controlling infectious diseases of human population.

作者信息

Kassa Semu Mitiku, Ouhinou Aziz

机构信息

Department of Mathematics, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia,

出版信息

J Math Biol. 2015 Jan;70(1-2):213-36. doi: 10.1007/s00285-014-0761-3. Epub 2014 Feb 11.

Abstract

A mathematical model for infectious disease epidemics with behaviour change and treatment is formulated and analysed. It is indicated that behaviour modification by the population has a significant impact on the dynamics of the disease. Moreover, an optimal control theory is applied to propose the best possible combination of efforts in controlling a disease. It is shown that it may not be necessary to continuously apply treatment at a full rate to eradicate the disease, if the effort is supported by effective behaviour modification strategies.

摘要

建立并分析了一个带有行为改变和治疗因素的传染病流行数学模型。结果表明,人群的行为改变对疾病动态有显著影响。此外,应用最优控制理论提出控制疾病的最佳努力组合。结果表明,如果有有效的行为改变策略支持,可能不必持续以全速率进行治疗来根除疾病。

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