Fowler F J, Wennberg J E, Timothy R P, Barry M J, Mulley A G, Hanley D
Center for Survey Research, University of Massachusetts, Boston.
JAMA. 1988 May 27;259(20):3018-22.
When prostatectomy is proposed as treatment for the symptoms of prostatism, the decision to operate should depend on how patients evaluate their symptoms and on objective information about the outcomes. We undertook a health interview study to determine the probabilities for symptom relief, improvement in the quality of life, and complications following surgery and to evaluate patient concern about the symptoms of prostatism. The operation was effective in reducing symptoms: 93% of severely and 79% of moderately symptomatic patients experienced improvement; however, a statistically significant improvement in indices of quality of life occurred only among patients with acute retention or severe symptoms prior to surgery. Short-term complications of varying severity occurred in 24% of patients; in addition, 4% reported persistent incontinence and 5%, impotence. Patients with similar symptoms reported considerable difference in the degree to which they were bothered by their symptoms. The result emphasizes the importance of patient participation in the decision to undergo prostatectomy.
当提议将前列腺切除术作为治疗前列腺增生症状的方法时,手术决策应取决于患者对自身症状的评估以及有关手术结果的客观信息。我们进行了一项健康访谈研究,以确定手术缓解症状、改善生活质量和出现并发症的概率,并评估患者对前列腺增生症状的担忧程度。手术在减轻症状方面是有效的:93%的重度症状患者和79%的中度症状患者症状得到改善;然而,生活质量指标在统计学上有显著改善的情况仅出现在术前有急性尿潴留或严重症状的患者中。24%的患者出现了不同严重程度的短期并发症;此外,4%的患者报告有持续性尿失禁,5%的患者报告有阳痿。有相似症状的患者在受症状困扰的程度上报告存在很大差异。这一结果强调了患者参与前列腺切除术决策的重要性。