Holstege G
Department of Anatomy, School of Medicine, University of California, San Francisco 94143.
Brain Res. 1988 Apr 26;447(1):154-8. doi: 10.1016/0006-8993(88)90977-8.
Injections with [3H]leucine in the ventral parabrachial nuclei and nucleus Kölliker-Fuse of the cat revealed strong projections to the nucleus raphe magnus (NRM) and adjacent tegmentum, while similar injections in the adjacent nucleus subcoeruleus produced diffuse projections to large parts of the tegmentum, but not specifically to the NRM. Horseradish peroxidase (HRP) injections in the area of the NRM and adjacent tegmentum demonstrated many labeled neurons in the ventral parabrachial nuclei, nucleus Kölliker-Fuse and nucleus subcoeruleus. These results suggest that the inhibition of nociception induced by stimulation in the ventral parabrachial nuclei may be based on the projections of this area to NRM and adjacent tegmentum.
用[3H]亮氨酸注射猫的腹侧臂旁核和 Kölliker-Fuse 核，显示出向中缝大核（NRM）和相邻被盖区有强烈投射，而在相邻的蓝斑下核进行类似注射时，产生向大部分被盖区的弥散投射，但并非特异性地投射到 NRM。在 NRM 区域和相邻被盖区注射辣根过氧化物酶（HRP），在腹侧臂旁核、Kölliker-Fuse 核和蓝斑下核中发现了许多标记神经元。这些结果表明，腹侧臂旁核刺激诱导的伤害感受抑制可能基于该区域向 NRM 和相邻被盖区的投射。
