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EMLA(®)乳膏作为用于鼻甲组织射频消融减容术的局部麻醉剂。

EMLA(®) cream as local anesthetic for radiofrequency turbinate tissue reduction.

作者信息

Martellucci Salvatore, Pagliuca Giulio, de Vincentiis Marco, Greco Antonio, Fusconi Massimo, De Virgilio Armando, Rosato Chiara, Gallo Andrea

机构信息

Department of Medico-Surgical Sciences and Biotechnologies, ENT Section, "Sapienza" University of Rome, Latina (LT), Italy,

出版信息

Eur Arch Otorhinolaryngol. 2014 Oct;271(10):2717-22. doi: 10.1007/s00405-014-2940-7. Epub 2014 Feb 21.

Abstract

Radiofrequency volumetric tissue reduction is a minimally invasive technique in the treatment of turbinate hypertrophy and is generally performed under local anesthesia. However, perioperative discomfort and pain are common side effects and studies concerning the technique of choice to anesthetize the nasal mucosa in this procedure are lacking. The aim of this prospective controlled trial is to assess the effectiveness of EMLA(®) cream as a topical anesthetic for radiofrequency volumetric tissue reduction of inferior turbinates comparing its effect with that obtained using a traditional anesthetic technique. 200 consecutive patients undergoing volumetric tissue reduction with topical anesthesia were enrolled. Patients were divided into two groups: Group A included 100 patients treated by placing cotton pledgets soaked with lidocaine 10% in the inferior meatus followed by the injection of 2% lidocaine into the head of the inferior turbinate; Group B included 100 patients treated with EMLA(®) cream. Patients were evaluated before and after surgery using rhinomanometry for obstructive symptoms. Four VAS about pain, troublesome swallowing, choking sensation and intraoperative anxiety were submitted to each patient immediately after surgery and after 2 months to assess various aspects of perioperative discomfort. A significant increase of nasal airflow was observed without differences between the two groups. Subjective evaluation regarding perioperative discomfort showed significant differences between Groups A and B immediately after surgery although it was less pronounced 2 months later. The results of this study suggest that EMLA(®) cream is an efficient tool in obtaining an adequate anesthetic effect in this procedure.

摘要

射频容积性组织减容术是治疗鼻甲肥大的一种微创技术,通常在局部麻醉下进行。然而,围手术期不适和疼痛是常见的副作用,且缺乏关于该手术中麻醉鼻黏膜的最佳技术的研究。这项前瞻性对照试验的目的是评估复方利多卡因乳膏作为局部麻醉剂用于下鼻甲射频容积性组织减容术的有效性,并将其效果与传统麻醉技术的效果进行比较。连续纳入200例接受局部麻醉下容积性组织减容术的患者。患者被分为两组:A组包括100例患者,治疗方法是在下鼻道放置浸有10%利多卡因的棉球,然后在下鼻甲头部注射2%利多卡因;B组包括100例使用复方利多卡因乳膏治疗的患者。术前和术后使用鼻阻力计评估患者的阻塞性症状。术后立即及术后2个月向每位患者提交关于疼痛、吞咽困难、哽咽感和术中焦虑的四项视觉模拟评分,以评估围手术期不适的各个方面。观察到两组患者鼻气流均显著增加,但两组之间无差异。关于围手术期不适的主观评估显示,术后A组和B组之间立即出现显著差异,尽管2个月后差异不那么明显。本研究结果表明,复方利多卡因乳膏是在此手术中获得充分麻醉效果的有效工具。

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