Lassus A, Kartamaa M, Happonen H P
Department of Venereology, University Central Hospital, Helsinki, Finland.
Sex Transm Dis. 1990 Jul-Sep;17(3):130-2. doi: 10.1097/00007435-199007000-00004.
Treatment of genital warts by laser surgery was performed in 100 male patients under local infiltration (2-6 ml 1% Xylocaine) or topical anesthesia with 2.5-7.5 ml EMLA cream. EMLA cream was applied to the warts ten minutes before the operation. Pain was significantly less during application of EMLA than during infiltration of Xylocaine. Infiltration anesthesia resulted in better surgical analgesia than EMLA, although the difference was small. The combined pain scores of application and surgery were significantly smaller in the EMLA group. The result suggests that EMLA applied for ten minutes constitutes a less painful treatment and is thus the anesthetic of choice for the laser surgery of genital warts.
对100例男性患者的尖锐湿疣采用激光手术治疗，手术在局部浸润麻醉（2 - 6毫升1%利多卡因）或外用2.5 - 7.5毫升复方利多卡因乳膏局部麻醉下进行。手术前10分钟将复方利多卡因乳膏涂抹于疣体上。涂抹复方利多卡因乳膏时的疼痛明显轻于利多卡因浸润时。浸润麻醉的手术镇痛效果优于复方利多卡因乳膏，尽管差异较小。复方利多卡因乳膏组涂抹和手术时的综合疼痛评分明显更低。结果表明，涂抹10分钟的复方利多卡因乳膏是一种疼痛较轻的治疗方法，因此是尖锐湿疣激光手术的首选麻醉剂。
