Fort Marta, Grimalt Joan O, Casas Maribel, Sunyer Jordi
Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research, Jordi Girona, 18., 08034, Barcelona, Catalonia, Spain.
Environ Sci Pollut Res Int. 2014 Oct;21(20):11689-98. doi: 10.1007/s11356-014-2614-4. Epub 2014 Feb 22.
Seafood consumption provides a significant amount of arsenic, although in its organic, nontoxic forms. Mediterranean populations may incorporate high levels of this metalloid as a consequence of seafood consumption. In the present study, the significance of this input among pregnant women from a Mediterranean city (Sabadell, Catalonia, Spain) is assessed. Total urinary arsenic was analyzed in 489 pairs of urine samples, corresponding to the 12th and 32 th weeks of pregnancy. Association of arsenic content with seafood and other dietary items were studied. Geometric mean concentrations were 34 and 37 μg/g creatinine during the first and third trimesters, respectively. The observed concentrations were similar to those reported in studies from other Mediterranean countries. The differences between both periods were not statistically significant. The only dietary factor significantly and positively associated with total urinary arsenic in both series of samples was seafood, particularly lean fish. Moreover, lean fish consumption during both periods was found to be the main determinant for differences in levels of arsenic between the first and third trimesters, which confirms the association between high levels of total urinary arsenic and seafood consumption.
食用海鲜会摄入大量砷，不过是以有机的、无毒的形式。地中海地区的人群由于食用海鲜，可能会摄入较高水平的这种类金属元素。在本研究中，评估了这种摄入量对于来自地中海城市（西班牙加泰罗尼亚萨瓦德尔）孕妇的意义。分析了489对尿液样本中的总尿砷含量，这些样本分别对应怀孕第12周和第32周。研究了砷含量与海鲜及其他饮食项目之间的关联。孕早期和孕晚期尿砷的几何平均浓度分别为34和37μg/g肌酐。观察到的浓度与其他地中海国家研究报告中的浓度相似。两个时期之间的差异无统计学意义。在这两组样本中，唯一与总尿砷显著正相关的饮食因素是海鲜，尤其是瘦鱼。此外，发现两个时期的瘦鱼消费量是孕早期和孕晚期砷水平差异的主要决定因素，这证实了总尿砷水平高与海鲜消费之间的关联。
