Sleath Betsy, Blalock Susan J, Covert David, Skinner Asheley Cockrell, Muir Kelly W, Robin Alan L
Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA ; Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, CB No. 7590, Chapel Hill, NC 27599-7590, USA.
Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
ISRN Ophthalmol. 2012 Oct 15;2012:902819. doi: 10.5402/2012/902819. eCollection 2012.
Objective. The objectives of the study were to (a) describe various factors potentially related to objectively measured adherence to glaucoma medications and self-reported glaucoma medication adherence self-efficacy and (b) examine the relationship between patient race, the number of patient reported-problems, and adherence in taking their glaucoma medication. This was a cross-sectional study conducted at two glaucoma subspecialist referral ophthalmology practices. Methods. We measured subjects' reported problems in using glaucoma medications, adherence to glaucoma medications utilizing the Medication Events Monitoring System (MEMS) devices, and general glaucoma medication adherence self-efficacy using a previously validated 10-item scale. Multivariable logistic and linear regression was used to analyze the data. Results. Seventy-one percent of patients self-reported at least one problem in using their glaucoma medications. White patients were more than 3 times more likely to be 80% adherent in using their glaucoma medications than non-White patients. Patients who had glaucoma longer reported significantly higher glaucoma medication adherence self-efficacy. Patients who reported more problems in using their medications had significantly lower glaucoma medication adherence self-efficacy. Conclusions. Eye care providers should assess patient reported problems and glaucoma medication adherence self-efficacy and work with patients to find ways to reduce the number of problems that patients experience to increase their self-efficacy in using glaucoma medications.
目的。本研究的目的是：(a) 描述与客观测量的青光眼药物依从性以及自我报告的青光眼药物依从性自我效能可能相关的各种因素；(b) 研究患者种族、患者报告的问题数量与青光眼药物服用依从性之间的关系。这是一项在两家青光眼专科转诊眼科诊所进行的横断面研究。方法。我们测量了受试者在使用青光眼药物方面报告的问题、使用药物事件监测系统（MEMS）设备测量的青光眼药物依从性，以及使用先前验证的10项量表测量的一般青光眼药物依从性自我效能。采用多变量逻辑回归和线性回归分析数据。结果。71%的患者自我报告在使用青光眼药物时至少存在一个问题。白人患者在使用青光眼药物时达到80%依从性的可能性是非白人患者的3倍多。患青光眼时间较长的患者报告的青光眼药物依从性自我效能显著更高。报告在使用药物方面存在更多问题的患者，其青光眼药物依从性自我效能显著更低。结论。眼科护理人员应评估患者报告的问题和青光眼药物依从性自我效能，并与患者合作，找到减少患者所经历问题数量的方法，以提高他们使用青光眼药物的自我效能。
