Gratziou Ch, Florou A, Ischaki E, Eleftheriou K, Sachlas A, Bersimis S, Zakynthinos S
Smoking Cessation Clinic, Pulmonary and Critical Care Department, Medical School, University of Athens, Athens, Greece.
Smoking Cessation Clinic, Pulmonary and Critical Care Department, Medical School, University of Athens, Athens, Greece.
Respir Med. 2014 Apr;108(4):577-83. doi: 10.1016/j.rmed.2014.01.007. Epub 2014 Feb 2.
Although smoking cessation is strongly indicated by international guidelines as an effective therapeutic tool for patients with COPD and Asthma, a large proportion of them do not quit smoking and they are regarded as a "difficult" target group.
To study the effectiveness of an intensive smoking cessation program in smokers with COPD and asthma under real-life conditions.
166 smokers with COPD, 120 smokers with asthma and 1854 control smokers attended the smoking cessation program in the out-patient patient Smoking Cessation Clinic of the Pulmonary Department in Athens University. Continuous Abstinence Rate (CAR) was evaluated in 3, 6, 9 and 12 months after the target quit date.
Short-term CAR (in 3 months) was 49.4% for COPD smokers, 51.7% for asthmatic smokers and 48.0% for the control group of smokers. 12 months after the initial visit the CAR was 13.9%, 18.3% and 15.9%, respectively. No statistically significant differences between groups at any study period were found. Smokers with good compliance with the program had higher long-term CAR after 12 months: 37.7% in COPD smokers, 40.0% in asthmatic smokers and 39.3% in control smokers. High CAR was observed at all stages of COPD severity.
The results support the view that smokers with respiratory obstructive airway diseases of any severity should be offered an intensive smoking cessation program with regular and long-term follow-up. This will help them to achieve high abstinence rates and prevent relapses.
尽管国际指南强烈建议戒烟是慢性阻塞性肺疾病(COPD)和哮喘患者的一种有效治疗手段,但其中很大一部分人并未戒烟,他们被视为“难”戒烟目标群体。
研究在实际生活条件下,强化戒烟计划对患有COPD和哮喘的吸烟者的有效性。
166名患有COPD的吸烟者、120名患有哮喘的吸烟者以及1854名对照吸烟者参加了雅典大学肺科门诊戒烟诊所的戒烟计划。在目标戒烟日期后的3、6、9和12个月评估持续戒烟率(CAR)。
COPD吸烟者的短期CAR(3个月时)为49.4%,哮喘吸烟者为51.7%,对照吸烟者为48.0%。初次就诊12个月后,CAR分别为13.9%、18.3%和15.9%。在任何研究期间,各组之间均未发现统计学上的显著差异。对该计划依从性良好的吸烟者在12个月后的长期CAR较高:COPD吸烟者为37.7%,哮喘吸烟者为40.0%,对照吸烟者为39.3%。在COPD严重程度的所有阶段均观察到高CAR。
结果支持这样一种观点,即应向任何严重程度的呼吸道阻塞性疾病吸烟者提供强化戒烟计划,并进行定期和长期随访。这将有助于他们实现高戒烟率并防止复吸。