利用相敏光学相干断层成像技术可视化超声激发的剪切波传播用于动态弹性成像。
Visualizing ultrasonically induced shear wave propagation using phase-sensitive optical coherence tomography for dynamic elastography.
出版信息
Opt Lett. 2014 Feb 15;39(4):838-41. doi: 10.1364/OL.39.000838.
Abstract
We report on the use of phase-sensitive optical coherence tomography (PhS-OCT) to detect and track temporal and spatial shear wave propagation within tissue, induced by ultrasound radiation force. Kilohertz-range shear waves are remotely generated in samples using focused ultrasound emission and their propagation is tracked using PhS-OCT. Cross-sectional maps of the local shear modulus are reconstructed from local estimates of shear wave speed in tissue-mimicking phantoms. We demonstrate the feasibility of combining ultrasound radiation force and PhS-OCT to perform high-resolution mapping of the shear modulus.
摘要
我们报告了使用相敏光学相干断层扫描（PhS-OCT）来检测和跟踪组织内超声辐射力引起的时变和空间剪切波传播。使用聚焦超声发射在样品中远程产生千赫兹范围内的剪切波，并使用 PhS-OCT 跟踪其传播。在组织模拟体模中，从组织中剪切波速度的局部估计值重建局部剪切弹性模量的横截面图。我们证明了将超声辐射力和 PhS-OCT 相结合进行剪切弹性模量的高分辨率映射的可行性。
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