声驱动光学相干弹性成像技术用于测量材料力学性能。
Acoustomotive optical coherence elastography for measuring material mechanical properties.
机构信息
Department of Electrical and Computer Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 405 North Mathews, Urbana, Illinois 61801, USA.
出版信息
Opt Lett. 2009 Oct 1;34(19):2894-6. doi: 10.1364/OL.34.002894.
Acoustomotive optical coherence elastography (AM-OCE), a dynamic and internal excitation optical coherence elastography technique, is reported. Acoustic radiation force was used for internal mechanical excitation, and spectral-domain optical coherence tomography was used for detection. Mechanical properties of gelatin tissue phantoms were measured by AM-OCE and verified using rheometry results. Measured mechanical properties including shear moduli and shear damping parameters of the gelatin samples double when their polymer concentration increases from 3% to 4%. Spectral analysis was also performed on the acquired data, which improved the processing speed by a factor of 5 compared with a least-square fitting approach. Quantitative measurement, microscale resolution, and remote excitation are the main features of AM-OCE, which make the technique promising for measuring biomechanical properties.
声驱动光学相干弹性成像（AM-OCE）是一种动态的内部激励光学相干弹性成像技术，本文对此进行了报道。该技术使用声辐射力进行内部机械激励，同时使用光谱域光学相干断层扫描进行检测。通过 AM-OCE 对明胶组织模型的力学性能进行了测量，并结合流变仪的结果进行了验证。实验结果表明，当聚合物浓度从 3%增加到 4%时，明胶样本的剪切模量和剪切阻尼参数均增加了一倍。此外，还对采集到的数据进行了光谱分析，与最小二乘拟合方法相比，该方法的处理速度提高了 5 倍。AM-OCE 的主要特点是定量测量、微尺度分辨率和远程激励，这使其有望用于测量生物力学特性。
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