a Faculty of Medicine and Health Sciences, Queen's Medical Centre , University of Nottingham , Clifton Boulevard , Nottingham , NG7 2RD , UK.
Crit Rev Food Sci Nutr. 2014;54(10):1322-9. doi: 10.1080/10408398.2011.635816.
In the contemporary society, diabetes mellitus is considered as a common, growing, serious, costly, and potentially preventable public health problem. It is forecasted that in 2030, the number of people with diabetes will go up from 117 million in 2000 to 366 million in 2030. The prevalence of diabetes will place a huge burden on health and financial structures of countries, and these will impact on individuals, as well as families and nations. Polysaccharides, para-aminobenzoic acid, fixed oils, sterol, proteins, and peptides are biologically active ingredients, which are found in pumpkins. The chemicals within pumpkins such as the fruit pulp, oil from ungerminated seeds, and protein from germinated seeds have hypoglycemic properties. Preliminary investigation showed that pumpkin seeds, and the macromolecules, therein, such as Trigonelline (TRG), Nicotinic acid (NA), and D-chiro-inositol (DCI), possess hypoglycemic properties and could assist in maintaining glycemic control.
在当代社会，糖尿病被认为是一种普遍存在、不断增长、严重、昂贵且潜在可预防的公共卫生问题。据预测，到 2030 年，糖尿病患者人数将从 2000 年的 1.17 亿上升到 2030 年的 3.66 亿。糖尿病的流行将给各国的卫生和财政结构带来巨大负担，这将影响个人、家庭和国家。多糖、对氨基苯甲酸、固定油、固醇、蛋白质和肽是在南瓜中发现的具有生物活性的成分。南瓜中的化学物质，如果肉、未发芽种子中的油和发芽种子中的蛋白质，具有降血糖作用。初步研究表明，南瓜籽及其大分子，如三磷酸肌醇（TRG）、烟酸（NA）和 D-手性肌醇（DCI），具有降血糖作用，有助于维持血糖控制。
