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本文引用的文献

1
Extended high-frequency thresholds in college students: effects of music player use and other recreational noise.大学生的扩展高频听力阈值:使用音乐播放器及其他娱乐噪音的影响。
J Am Acad Audiol. 2013 Sep;24(8):725-39. doi: 10.3766/jaaa.24.8.9.
2
Age-related cochlear synaptopathy: an early-onset contributor to auditory functional decline.年龄相关性耳蜗突触病:听觉功能下降的早期发病因素。
J Neurosci. 2013 Aug 21;33(34):13686-94. doi: 10.1523/JNEUROSCI.1783-13.2013.
3
Efferent feedback minimizes cochlear neuropathy from moderate noise exposure.传出反馈可最大限度减少中度噪声暴露引起的耳蜗神经病变。
J Neurosci. 2013 Mar 27;33(13):5542-52. doi: 10.1523/JNEUROSCI.5027-12.2013.
4
Impulse noise generated by starter pistols.发令枪产生的脉冲噪声。
Int J Audiol. 2013 Feb;52 Suppl 1(0 1):S9-19. doi: 10.3109/14992027.2012.745650.
5
The effect of alpha-lipoic acid on temporary threshold shift in humans: a preliminary study.α-硫辛酸对人体瞬态阈值偏移的影响:一项初步研究。
Acta Otorhinolaryngol Ital. 2012 Dec;32(6):380-5.
6
The cochlea magnesium content is negatively correlated with hearing loss induced by impulse noise.耳蜗内镁含量与脉冲噪声引起的听力损失呈负相关。
Am J Otolaryngol. 2013 May-Jun;34(3):209-15. doi: 10.1016/j.amjoto.2012.11.015. Epub 2013 Jan 16.
7
Digital music exposure reliably induces temporary threshold shift in normal-hearing human subjects.数字音乐暴露确实会引起正常听力人类受试者的暂时阈移。
Ear Hear. 2012 Nov-Dec;33(6):e44-58. doi: 10.1097/AUD.0b013e31825f9d89.
8
Sound medicine.合理的医学。
Nat Med. 2012 May 4;18(5):642-5. doi: 10.1038/nm0512-642.
9
Effects of repeated "benign" noise exposures in young CBA mice: shedding light on age-related hearing loss.反复“良性”噪声暴露对幼年 CBA 小鼠的影响:揭示年龄相关性听力损失。
J Assoc Res Otolaryngol. 2012 Aug;13(4):505-15. doi: 10.1007/s10162-012-0329-0. Epub 2012 Apr 25.
10
Leupeptin reduces impulse noise induced hearing loss.亮抑酶肽可减轻脉冲噪声诱发的听力损失。
J Occup Med Toxicol. 2011 Dec 29;6:38. doi: 10.1186/1745-6673-6-38.

玩视频游戏期间受脉冲噪声影响后的暂时阈移:实验室数据。

Temporary threshold shift after impulse-noise during video game play: laboratory data.

机构信息

Department of Speech, Language, and Hearing Sciences, University of Florida , Gainesville , USA.

出版信息

Int J Audiol. 2014 Mar;53 Suppl 2(0 2):S53-65. doi: 10.3109/14992027.2013.865844.

DOI:10.3109/14992027.2013.865844
PMID:24564694
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4698154/
Abstract

OBJECTIVE

Prevention of temporary threshold shift (TTS) after laboratory-based exposure to pure-tones, broadband noise, and narrowband noise signals has been achieved, but prevention of TTS under these experimental conditions may not accurately reflect protection against hearing loss following impulse noise. This study used a controlled laboratory-based TTS paradigm that incorporated impulsive stimuli into the exposure protocol; development of this model could provide a novel platform for assessing proposed therapeutics.

DESIGN

Participants played a video game that delivered gunfire-like sound through headphones as part of a target practice game. Effects were measured using audiometric threshold evaluations and distortion product otoacoustic emissions (DPOAEs). The sound level and number of impulses presented were sequentially increased throughout the study.

STUDY SAMPLE

Participants were normal-hearing students at the University of Florida who provided written informed consent prior to participation.

RESULTS

TTS was not reliably induced by any of the exposure conditions assessed here. However, there was significant individual variability, and a subset of subjects showed TTS under some exposure conditions.

CONCLUSIONS

A subset of participants demonstrated reliable threshold shifts under some conditions. Additional experiments are needed to better understand and optimize stimulus parameters that influence TTS after simulated impulse noise.

摘要

目的

在基于实验室的纯音、宽带噪声和窄带噪声信号暴露后,已实现了对暂时阈移(TTS)的预防,但在这些实验条件下预防 TTS 可能无法准确反映对脉冲噪声引起的听力损失的保护。本研究使用了一种基于实验室的受控 TTS 范式,该范式将脉冲刺激纳入暴露方案中;该模型的开发可为评估拟议治疗方法提供新的平台。

设计

参与者通过耳机玩了一个类似于枪声的视频游戏,作为靶场练习游戏的一部分。使用听力阈值评估和畸变产物耳声发射(DPOAE)来测量效果。在整个研究过程中,声级和脉冲数逐渐增加。

研究样本

参与者是佛罗里达大学听力正常的学生,他们在参与前提供了书面知情同意书。

结果

这里评估的任何暴露条件均未可靠地引起 TTS。然而,存在显著的个体差异,并且一部分受试者在某些暴露条件下出现 TTS。

结论

一部分参与者在某些条件下表现出可靠的阈值变化。需要进行更多的实验来更好地理解和优化影响模拟脉冲噪声后 TTS 的刺激参数。