Department of Dermatology, Health Sciences Faculty, Roskilde Hospital, University of Copenhagen, , Copenhagen, Denmark.
Postgrad Med J. 2014 Apr;90(1062):216-21; quiz 220. doi: 10.1136/postgradmedj-2013-131994. Epub 2014 Feb 24.
Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin condition that typically occurs after puberty. The primary clinical presentation is painful inflamed nodules or boils in the apocrine gland-bearing regions (armpits, genital area, groin, breasts and buttocks/anus) that progress to abscesses, sinus tracts and scarring. Severity is typically described according to three Hurley categories, with most patients having mild or moderate disease. Estimated prevalence is 1-4% worldwide and HS is three times more common in women than men. Patients' disease burden includes intense pain, work disability and overall poor quality of life. Although the clinical signs of the disease can often be hidden by clothing, active HS is associated with a malodorous discharge that contributes to the disabling social stigma. Risk factors include smoking and obesity. Comorbidities include inflammatory bowel disease and spondyloarthropathies. The presentation of the disease is distinct, yet HS is not well-recognised except in dermatology clinics.
化脓性汗腺炎（HS）是一种慢性、复发性、炎症性皮肤病，通常发生在青春期后。主要临床表现为在顶泌汗腺分布区域（腋窝、生殖器、腹股沟、乳房和臀部/肛门）出现疼痛性炎症性结节或脓肿，进展为脓肿、窦道和瘢痕。严重程度通常根据 Hurley 三个类别来描述，大多数患者的疾病为轻度或中度。全球估计患病率为 1-4%，HS 在女性中的发病率是男性的三倍。患者的疾病负担包括剧烈疼痛、工作能力丧失和整体生活质量差。尽管疾病的临床症状通常可以被衣物隐藏，但活动性 HS 会伴有恶臭分泌物，导致严重的社会污名。危险因素包括吸烟和肥胖。合并症包括炎症性肠病和脊柱关节炎。该疾病的表现很明显，但除了皮肤科诊所外，HS 并没有得到很好的认识。
