瘢痕性类狼疮样脱发与甲状腺疾病的相关性：一项回顾性病例对照研究。
Association of lichen planopilaris with thyroid disease: a retrospective case-control study.
机构信息
Department of Dermatology and Dermatopathology, Cleveland Clinic, Cleveland, Ohio.
Department of Dermatology and Dermatopathology, Cleveland Clinic, Cleveland, Ohio.
出版信息
J Am Acad Dermatol. 2014 May;70(5):889-92. doi: 10.1016/j.jaad.2013.12.014. Epub 2014 Feb 22.
BACKGROUND
Studies on the precise causes and comorbidities seen with lichen planopilaris (LPP) are limited.
OBJECTIVE
We sought to determine the prevalence of thyroid diseases in patients with LPP.
METHODS
Medical records of 166 patients with LPP and 81 age- and gender-matched control subjects seen in the Department of Dermatology at the Cleveland Clinic Foundation in Ohio between 2000 and 2013 were reviewed.
RESULTS
A diagnosis of thyroid disease was present in 34% (n = 57) of the 166 patients with LPP, and in 11% (n = 9) of the control subjects (P = .0001). When confined to hypothyroidism only, this disease was found in 29% (n = 48) of the patients with LPP and 9% (n = 7) of the control subjects (P = .0003).
LIMITATIONS
This study was limited by being retrospective.
CONCLUSION
In our patients, LPP was associated with thyroid disease, especially hypothyroidism.
背景
关于扁平苔藓（LPP）的确切病因和合并症的研究有限。
目的
我们旨在确定 LPP 患者中甲状腺疾病的患病率。
方法
回顾了 2000 年至 2013 年间在俄亥俄州克利夫兰诊所基金会皮肤科就诊的 166 例 LPP 患者和 81 例年龄和性别匹配的对照者的病历。
结果
166 例 LPP 患者中有 34%（n=57）诊断为甲状腺疾病，而对照组中为 11%（n=9）（P=0.0001）。仅局限于甲状腺功能减退症时，LPP 患者中这一疾病的患病率为 29%（n=48），而对照组中为 9%（n=7）（P=0.0003）。
局限性
本研究受到回顾性的限制。
结论
在我们的患者中，LPP 与甲状腺疾病相关，尤其是甲状腺功能减退症。
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