Kopylov Uri, Seidman Ernest G
Uri Kopylov, Ernest G Seidman, Division of Gastroenterology, McGill University Health Center, Montreal, Quebec H3G A14, Canada.
World J Gastroenterol. 2014 Feb 7;20(5):1155-64. doi: 10.3748/wjg.v20.i5.1155.
Videocapsule endoscopy (VCE) has revolutionized our ability to visualize the small bowel mucosa. This modality is a valuable tool for the diagnosis of obscure small bowel Crohn's disease (CD), and can also be used for monitoring of disease activity in patients with established small-bowel CD, detection of complications such as obscure bleeding and neoplasms, evaluation of response to anti-inflammatory treatment and postoperative recurrence following small bowel resection. VCE could also be an important tool in the management of patients with unclassified inflammatory bowel disease, potentially resulting in reclassification of these patients as having CD. Reports on postoperative monitoring and evaluation of patients with ileal pouch-anal anastomosis who have developed pouchitis have recenty been published. Monitoring of colonic inflammatory activity in patients with ulcerative colitis using the recently developed colonic capsule has also been reported. Capsule endoscopy is associated with an excellent safety profile. Although retention risk is increased in patients with small bowel CD, this risk can be significanty decreased by a routine utilization of a dissolvable patency capsule preceding the ingestion of the diagnostic capsule. This paper contains an overview of the current and future clinical applications of capsule endoscopy in inflammatory bowel disease.
视频胶囊内镜检查（VCE）彻底改变了我们观察小肠黏膜的能力。这种检查方式是诊断不明原因小肠克罗恩病（CD）的宝贵工具，也可用于监测已确诊小肠CD患者的疾病活动情况、检测诸如隐匿性出血和肿瘤等并发症、评估抗炎治疗的反应以及小肠切除术后的复发情况。VCE在未分类的炎症性肠病患者的管理中也可能是一项重要工具，这有可能使这些患者重新分类为患有CD。近期已发表了关于回肠储袋肛管吻合术后患者的术后监测和评估的报告。也有报道称使用最近研发的结肠胶囊对溃疡性结肠炎患者的结肠炎症活动进行监测。胶囊内镜检查具有出色的安全性。虽然小肠CD患者的胶囊滞留风险会增加，但在摄入诊断性胶囊之前常规使用可溶解的通畅胶囊可显著降低这种风险。本文概述了胶囊内镜检查在炎症性肠病中的当前及未来临床应用。
