Moretuzzo R W, DiLauro S, Jenison E, Chen S L, Reindollar R H, McDonough P G
Department of Obstetrics and Gynecology, Akron General Medical Center, Ohio 44307.
Fertil Steril. 1988 Sep;50(3):430-3. doi: 10.1016/s0015-0282(16)60127-9.
Serum and peritoneal lavage fluid CA-125 levels were assayed in 20 women with endometriosis and 20 control women at the time of laparoscopy. Serum levels of CA-125 were significantly higher in women with endometriosis. Peritoneal lavage fluid CA-125 levels were significantly higher than serum levels but showed no significant difference between control and endometriosis patients. Peritoneal lavage fluid CA-125 did not follow expected dilution curves when attempts were made to validate the assay. Serum CA-125 levels were a more sensitive indicator of endometriosis, than peritoneal lavage fluid CA-125 levels.
在腹腔镜检查时，对20名患有子宫内膜异位症的女性和20名对照女性的血清及腹腔灌洗液中的CA - 125水平进行了测定。患有子宫内膜异位症的女性血清CA - 125水平显著更高。腹腔灌洗液中CA - 125水平显著高于血清水平，但对照患者和子宫内膜异位症患者之间无显著差异。当试图验证该检测方法时，腹腔灌洗液CA - 125并不遵循预期的稀释曲线。血清CA - 125水平比腹腔灌洗液CA - 125水平更能敏感地指示子宫内膜异位症。
