Patton P E, Field C S, Harms R W, Coulam C B
Fertil Steril. 1986 Jun;45(6):770-3. doi: 10.1016/s0015-0282(16)49390-8.
CA-125 is a cellular antigen detected in many patients with ovarian cancer, but it has also been detected in patients with endometriosis. Preoperative CA-125 levels were drawn from 113 patients before they underwent laparoscopy. Patients were categorized into diagnostic groups on the basis of pathologic findings. CA-125 levels in patients with evidence of intraabdominal adhesions were not statistically different from those in patients with normal pelvic anatomy. However, patients with advanced endometriosis had significantly elevated levels of CA-125 when compared with patients with normal pelvic anatomy (P less than 0.05). The clinical and immunologic implications of elevated CA-125 levels in patients with advanced endometriosis are discussed.
CA - 125是一种在许多卵巢癌患者中检测到的细胞抗原，但在子宫内膜异位症患者中也有检测到。在113例患者进行腹腔镜检查前抽取其术前CA - 125水平。根据病理结果将患者分为不同的诊断组。有腹腔内粘连证据的患者的CA - 125水平与盆腔解剖结构正常的患者相比无统计学差异。然而，与盆腔解剖结构正常的患者相比，晚期子宫内膜异位症患者的CA - 125水平显著升高（P小于0.05）。本文讨论了晚期子宫内膜异位症患者CA - 125水平升高的临床和免疫学意义。
