Bradley Beverly D, Howie Stephen R C, Chan Timothy C Y, Cheng Yu-Ling
Centre for Global Engineering, University of Toronto, Toronto, Canada ; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada.
Child Survival Theme, Medical Research Council Unit, The Gambia, Banjul, The Gambia.
PLoS One. 2014 Feb 20;9(2):e89872. doi: 10.1371/journal.pone.0089872. eCollection 2014.
Planning for the reliable and cost-effective supply of a health service commodity such as medical oxygen requires an understanding of the dynamic need or 'demand' for the commodity over time. In developing country health systems, however, collecting longitudinal clinical data for forecasting purposes is very difficult. Furthermore, approaches to estimating demand for supplies based on annual averages can underestimate demand some of the time by missing temporal variability.
A discrete event simulation model was developed to estimate variable demand for a health service commodity using the important example of medical oxygen for childhood pneumonia. The model is based on five key factors affecting oxygen demand: annual pneumonia admission rate, hypoxaemia prevalence, degree of seasonality, treatment duration, and oxygen flow rate. These parameters were varied over a wide range of values to generate simulation results for different settings. Total oxygen volume, peak patient load, and hours spent above average-based demand estimates were computed for both low and high seasons.
Oxygen demand estimates based on annual average values of demand factors can often severely underestimate actual demand. For scenarios with high hypoxaemia prevalence and degree of seasonality, demand can exceed average levels up to 68% of the time. Even for typical scenarios, demand may exceed three times the average level for several hours per day. Peak patient load is sensitive to hypoxaemia prevalence, whereas time spent at such peak loads is strongly influenced by degree of seasonality.
A theoretical study is presented whereby a simulation approach to estimating oxygen demand is used to better capture temporal variability compared to standard average-based approaches. This approach provides better grounds for health service planning, including decision-making around technologies for oxygen delivery. Beyond oxygen, this approach is widely applicable to other areas of resource and technology planning in developing country health systems.
规划诸如医用氧气这类卫生服务商品的可靠且具成本效益的供应,需要了解该商品随时间变化的动态需求或“需求量”。然而,在发展中国家的卫生系统中,为预测目的收集纵向临床数据非常困难。此外,基于年度平均值估算供应需求的方法有时会因忽略时间变异性而低估需求。
开发了一个离散事件模拟模型,以儿童肺炎用医用氧气这一重要实例来估算卫生服务商品的可变需求。该模型基于影响氧气需求的五个关键因素:年度肺炎住院率、低氧血症患病率、季节性程度、治疗持续时间和氧气流速。这些参数在很宽的取值范围内变化,以生成不同场景的模拟结果。计算了淡季和旺季的总氧气量、患者高峰负荷以及高于基于平均需求估计值的时长。
基于需求因素年度平均值的氧气需求估计常常会严重低估实际需求。对于低氧血症患病率和季节性程度较高的场景,需求可能在高达68%的时间内超过平均水平。即使对于典型场景,需求也可能每天有几个小时超过平均水平的三倍。患者高峰负荷对低氧血症患病率敏感,而处于此类高峰负荷的时长则受季节性程度的强烈影响。
本文提出了一项理论研究,与基于标准平均值的方法相比,采用模拟方法估算氧气需求能更好地捕捉时间变异性。这种方法为卫生服务规划提供了更好的依据,包括围绕氧气输送技术的决策。除氧气外,这种方法广泛适用于发展中国家卫生系统中资源和技术规划的其他领域。