Seo Young Seok, Kim Mi-Sook, Yoo Hyung-Jun, Jang Won-Il
Young Seok Seo, Mi-Sook Kim, Hyung-Jun Yoo, Won-Il Jang, Department of Radiation Oncology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul 139-706, South Korea.
World J Gastroenterol. 2014 Feb 28;20(8):2005-13. doi: 10.3748/wjg.v20.i8.2005.
Recurrence of colorectal cancer (CRC) often presents as solitary metastases, oligometastases or oligo-recurrence. Surgical resection became the preferred treatment for patients with CRC lung and hepatic metastases. However, surgical treatment for oligo-recurrence within nodal area is not a widely accepted treatment due to due to their relative rarity and high postoperative morbidity. Stereotactic body radiotherapy (SBRT) is one of the emerging radiation treatment techniques in which a high radiation dose can be delivered to the tumor. High-dose SBRT can ablate the tumor with an efficacy similar to that achieved with surgery, especially for small tumors. However, there have been very few studies on SBRT for oligo-recurrence within nodal area, although several studies have evaluated the role of SBRT in the treatment of liver and lung metastases from CRC. This article reviews the current clinical status of and treatment methods for oligo-recurrence within nodal area from CRC, with particular emphasis on SBRT.
结直肠癌（CRC）复发常表现为孤立性转移、寡转移或寡复发。手术切除已成为CRC肺和肝转移患者的首选治疗方法。然而，由于其相对罕见且术后发病率高，针对区域淋巴结内寡复发的手术治疗并未被广泛接受。立体定向体部放疗（SBRT）是一种新兴的放射治疗技术，可向肿瘤输送高剂量辐射。高剂量SBRT可消融肿瘤，其疗效与手术相当，尤其适用于小肿瘤。然而，尽管有几项研究评估了SBRT在CRC肝和肺转移治疗中的作用，但针对区域淋巴结内寡复发的SBRT研究却非常少。本文综述了CRC区域淋巴结内寡复发的当前临床现状及治疗方法，尤其侧重于SBRT。
