Posokhov Igor N, Konradi Aleksandra O, Shlyakhto Eugeny V, Mamontov Oleg V, Orlov Artemy V, Rogoza Anatoly N
Hemodynamic Laboratory Ltd, Nizhniy Novgorod, Moscow, Russia.
Almazov Federal Heart, Blood and Endocrinology Centre, Saint Petersburg, Moscow, Russia.
Med Devices (Auckl). 2014 Feb 27;7:29-33. doi: 10.2147/MDER.S58507. eCollection 2014.
The pulse wave velocity (PWV) threshold for hypertensive target organ damage is presently set at 10 meters per second. New 24-hour monitors (eg, BPLab® and Vasotens®) provide several PWV measurements over a period of 24-72 hours. A new parameter, ie, the Pulse Time Index of Norm (PTIN), can be calculated from these data. The PTIN is defined as the percentage of a 24-hour period during which the PWV does not exceed 10 meters per second. The aim of the present study was to test the new PTIN for clinical feasibility using day-to-day repeatability analysis. Oscillometrically generated waveform files (n=85), which were previously used for research studies, were reanalyzed using the new 2013 version software of the Vasotens technology program, which enables calculation of PTIN. The intraclass correlation coefficient was 0.98 and Cronbach's alpha was 0.97, indicating that the PTIN has excellent day-to-day repeatability and internal consistency. The present results show adequate repeatability, and PTIN assessment using the Vasotens technology appears to be feasible.
目前，高血压靶器官损害的脉搏波速度（PWV）阈值设定为每秒10米。新型24小时监测仪（如BPLab®和Vasotens®）可在24至72小时内进行多次PWV测量。根据这些数据可以计算出一个新参数，即正常脉搏时间指数（PTIN）。PTIN定义为24小时内PWV不超过每秒10米的时间段所占的百分比。本研究的目的是通过日常重复性分析来测试新的PTIN在临床应用中的可行性。使用Vasotens技术程序的2013版新软件对先前用于研究的示波法生成的波形文件（n = 85）进行重新分析，该软件能够计算PTIN。组内相关系数为0.98，Cronbach's α系数为0.97，表明PTIN具有出色的日常重复性和内部一致性。目前的结果显示出足够的重复性，使用Vasotens技术评估PTIN似乎是可行的。
