Zhao Hansheng, Peng Zhenhua, Fei Benhua, Li Lubin, Hu Tao, Gao Zhimin, Jiang Zehui
State Forestry Administration Key Open Laboratory on the Science and Technology of Bamboo and Rattan, International Center for Bamboo and Rattan, Beijing 100102, China, State key laboratory of tree genetics and breeding, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China and Key Laboratory of Tree Breeding and Cultivation, State Forestry Administration, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China.
Database (Oxford). 2014 Mar 5;2014:bau006. doi: 10.1093/database/bau006. Print 2014.
Bamboo, as one of the most important non-timber forest products and fastest-growing plants in the world, represents the only major lineage of grasses that is native to forests. Recent success on the first high-quality draft genome sequence of moso bamboo (Phyllostachys edulis) provides new insights on bamboo genetics and evolution. To further extend our understanding on bamboo genome and facilitate future studies on the basis of previous achievements, here we have developed BambooGDB, a bamboo genome database with functional annotation and analysis platform. The de novo sequencing data, together with the full-length complementary DNA and RNA-seq data of moso bamboo composed the main contents of this database. Based on these sequence data, a comprehensively functional annotation for bamboo genome was made. Besides, an analytical platform composed of comparative genomic analysis, protein-protein interactions network, pathway analysis and visualization of genomic data was also constructed. As discovery tools to understand and identify biological mechanisms of bamboo, the platform can be used as a systematic framework for helping and designing experiments for further validation. Moreover, diverse and powerful search tools and a convenient browser were incorporated to facilitate the navigation of these data. As far as we know, this is the first genome database for bamboo. Through integrating high-throughput sequencing data, a full functional annotation and several analysis modules, BambooGDB aims to provide worldwide researchers with a central genomic resource and an extensible analysis platform for bamboo genome. BambooGDB is freely available at http://www.bamboogdb.org/. Database URL: http://www.bamboogdb.org.
竹子是世界上最重要的非木材森林产品之一,也是生长最快的植物之一,是唯一原产于森林的主要禾本科谱系。最近毛竹(Phyllostachys edulis)高质量草图基因组序列的成功绘制为竹子遗传学和进化提供了新见解。为了进一步拓展我们对竹子基因组的理解,并在前人成果的基础上推动未来研究,我们开发了BambooGDB,一个具有功能注释和分析平台的竹子基因组数据库。该数据库的主要内容包括从头测序数据,以及毛竹的全长互补DNA和RNA测序数据。基于这些序列数据,对竹子基因组进行了全面的功能注释。此外,还构建了一个由比较基因组分析、蛋白质-蛋白质相互作用网络、通路分析和基因组数据可视化组成的分析平台。作为理解和识别竹子生物学机制的发现工具,该平台可作为一个系统框架,帮助设计实验并进行进一步验证。此外,还集成了多样且强大的搜索工具和便捷的浏览器,以方便浏览这些数据。据我们所知,这是首个竹子基因组数据库。通过整合高通量测序数据、全面的功能注释和多个分析模块,BambooGDB旨在为全球研究人员提供一个核心基因组资源以及一个可扩展的竹子基因组分析平台。BambooGDB可在http://www.bamboogdb.org/免费获取。数据库网址:http://www.bamboogdb.org。