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芦荟漱口水对牙周健康的影响:三盲随机对照试验。

Effect of Aloe vera mouthwash on periodontal health: triple blind randomized control trial.

作者信息

Karim Bushra, Bhaskar Dara John, Agali Chandan, Gupta Devanand, Gupta Rajendra Kumar, Jain Ankita, Kanwar Alpana

机构信息

Post graduate student, Department of Public Health Dentistry, Teerthankar Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India; Tel: +91-9808683192; e-mail:

出版信息

Oral Health Dent Manag. 2014 Mar;13(1):14-9.

Abstract

BACKGROUND

With the increasing incidence of periodontal diseases and development of antibiotic resistance, the global need for alternative treatment modalities, safe, effective, and economical products is the need of time. Aloe vera is a medicinal plant which has the greater medicinal value and enormous properties for curing and preventing oral diseases disease.

AIM

The aim of the study was to access the effect of Aloe vera mouthwash on the dental plaque and gingivitis and comparing it with the bench mark control chlorhexidine and placebo.

MATERIAL AND METHODS

345 healthy subjects were randomly allocated in 3 groups to the test group (n=115) - mouthwash containing Aloe vera, Control group (n=115) -chlorhexidene group, Distilled water - Placebo (n=115) . Plaque Index (PI) and Gingival Index (GI) were assessed at days 0, 15 and 30. Subjects were asked to rinse their mouth with the stated mouthwash, twice a day, during a 30-day period.

RESULTS

Our result showed that Aloe vera mouthrinse is equally effective in reducing periodontal indices as Chlorhexidine. The results demonstrated a significant reduction of gingival bleeding and plaque indices in both groups over a period of 15 and 30 days as compared to placebo group. There was a significant reduction on plaque and gingivitis in Aloe vera and chlorhexidine groups and no statistically significant difference was observed among them (p>0.05). Aloe vera mouthwash showed no side effects as seen with chlorhexidine.

CONCLUSION

The results of the present study indicate that Aloe vera may prove to be an effective mouthwash owing to its ability in reducing periodontal indices.

摘要

背景

随着牙周疾病发病率的上升以及抗生素耐药性的发展,全球对替代治疗方式、安全、有效且经济的产品的需求日益迫切。芦荟是一种具有较高药用价值且具备治疗和预防口腔疾病多种特性的药用植物。

目的

本研究旨在评估芦荟漱口水对牙菌斑和牙龈炎的影响,并将其与作为基准对照的洗必泰和安慰剂进行比较。

材料与方法

345名健康受试者被随机分为3组,试验组(n = 115)——含芦荟的漱口水组,对照组(n = 115)——洗必泰组,蒸馏水——安慰剂组(n = 115)。在第0天、第15天和第30天评估菌斑指数(PI)和牙龈指数(GI)。受试者被要求在30天内每天用规定的漱口水漱口两次。

结果

我们的结果表明,芦荟漱口水在降低牙周指数方面与洗必泰同样有效。结果显示,与安慰剂组相比,两组在15天和30天期间牙龈出血和菌斑指数均显著降低。芦荟组和洗必泰组的菌斑和牙龈炎均显著降低,且两组之间未观察到统计学上的显著差异(p>0.05)。芦荟漱口水未显示出洗必泰那样的副作用。

结论

本研究结果表明,芦荟因其降低牙周指数的能力可能被证明是一种有效的漱口水。

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