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后房型有晶状体眼人工晶状体植入术后角膜生物力学参数的临床评估。

Clinical evaluation of corneal biomechanical parameters after posterior chamber phakic intraocular lens implantation.

机构信息

*Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan; and †Department of Ophthalmology, Faculty of Medicine, Minia University Hospitals, Minia, Egypt.

出版信息

Cornea. 2014 May;33(5):470-4. doi: 10.1097/ICO.0000000000000088.

Abstract

PURPOSE

The aim of this study was to quantitatively assess the changes in corneal biomechanics after posterior chamber phakic intraocular lens (Visian ICL; STAAR Surgical) implantation for normal and keratoconic subjects.

METHODS

We retrospectively examined 29 eyes of 16 consecutive patients (mean age ± SD, 32.4 ± 7.3 years) undergoing implantable collamer lens (ICL) implantation through a 3.0-mm temporal corneal incision. We longitudinally assessed the values of corneal hysteresis (CH) and corneal resistance factor (CRF) using an Ocular Response Analyzer. We also investigated the relationship between these biomechanical parameters and central corneal thickness (CCT) preoperatively, and at 1 week, 1 month, and 3 months postoperatively.

RESULTS

The CH was 9.2 ± 1.4 mm Hg preoperatively, and 9.2 ± 1.4 mm Hg, 9.3 ± 1.7 mm Hg, and 8.8 ± 1.3 mm Hg at 1 week, 1 month, and 3 months postoperatively, respectively. The CRF was 8.4 ± 1.6 mm Hg preoperatively, and 9.0 ± 1.5 mm Hg, 8.8 ± 1.7 mm Hg, and 8.8 ± 1.6 mm Hg, at 1 week, 1 month, and 3 months postoperatively, respectively. Multiple comparisons demonstrated no significant differences between measurements made preoperatively and postoperatively (P > 0.05, Dunnett test). Both CH and CRF were significantly correlated with CCT 3 months postoperatively [Spearman correlation coefficient (r) = 0.48, P = 0.01 for CH; r = 0.84, P < 0.001 for CRF].

CONCLUSIONS

We found no significant changes in CH or CRF after ICL implantation, not only in normal eyes but also in keratoconic eyes, suggesting that this surgical technique does not significantly affect corneal biomechanical factors. The CCT may play some role in corneal biomechanics even in eyes undergoing ICL implantation.

摘要

目的

本研究旨在定量评估正常眼和圆锥角膜患者行后房房角固定型有晶状体眼人工晶状体(Visian ICL;STAAR Surgical)植入术后角膜生物力学的变化。

方法

我们回顾性分析了 16 例(平均年龄 ± 标准差,32.4 ± 7.3 岁)连续患者的 29 只眼,这些患者均通过 3.0mm 颞侧角膜切口行可植入式隐形眼镜(ICL)植入术。我们使用眼反应分析仪(ORA)纵向评估了角膜滞后量(CH)和角膜阻力因子(CRF)的值。我们还研究了这些生物力学参数与术前、术后 1 周、1 个月和 3 个月时的中央角膜厚度(CCT)之间的关系。

结果

术前 CH 值为 9.2 ± 1.4mmHg,术后分别为 9.2 ± 1.4mmHg、9.3 ± 1.7mmHg 和 8.8 ± 1.3mmHg。术前 CRF 值为 8.4 ± 1.6mmHg,术后分别为 9.0 ± 1.5mmHg、8.8 ± 1.7mmHg 和 8.8 ± 1.6mmHg。多次比较显示术前与术后测量值之间无显著差异(P>0.05,Dunnett 检验)。CH 和 CRF 均与术后 3 个月时的 CCT 显著相关[Spearman 相关系数(r)=0.48,P=0.01 对 CH;r=0.84,P<0.001 对 CRF]。

结论

我们发现 ICL 植入术后 CH 或 CRF 无显著变化,不仅在正常眼中,在圆锥角膜眼中也是如此,这表明该手术技术不会显著影响角膜生物力学因素。即使在接受 ICL 植入术的眼中,CCT 可能在角膜生物力学中也发挥一定作用。

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