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评价白内障超声乳化吸除联合角巩膜缘松解切口术对角膜生物力学参数的影响。

Evaluation of corneal biomechanical parameters after simultaneous phacoemulsification with intraocular lens implantation and limbal relaxing incisions.

机构信息

Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan.

出版信息

J Cataract Refract Surg. 2011 Feb;37(2):265-70. doi: 10.1016/j.jcrs.2010.08.045.

DOI:10.1016/j.jcrs.2010.08.045
PMID:21241908
Abstract

PURPOSE

To determine whether alterations in architecture cause corneal biomechanical changes after simultaneous cataract surgery and limbal relaxing incisions (LRIs).

SETTING

Department of Ophthalmology, Kitasato University, Kanagawa, Japan.

DESIGN

Observational case series.

METHODS

This study longitudinally assessed corneal hysteresis (CH) and the corneal resistance factor (CRF) using the Ocular Response Analyzer in eyes having cataract surgery with LRIs. The relationship between these biomechanical parameters and central corneal thickness (CCT), measured using an ultrasound pachymeter, was also assessed.

RESULTS

The mean CH was 10.0 mm Hg ± 1.2 (SD) preoperatively, 9.0 ± 1.6 mm Hg 1 day postoperatively, 9.7 ± 1.4 mm Hg at 1 week, 9.6 ± 1.4 mm Hg at 1 month, and 10.2 ± 1.3 mm Hg at 3 months. The mean CRF was 10.0 ± 1.5 mm Hg, 8.9 ± 1.6 mm Hg, 9.5 ± 1.5 mm Hg, 9.5 ± 1.4 mm Hg, and 9.5 ± 1.4 mm Hg, respectively. There were significant differences between preoperative and 1-day postoperative measurements (P=.005, CH; P=.004, CRF). The CH and CRF were significantly correlated with CCT (r = 0.33, P=.04 and r = 0.40, P=.01, respectively) 3 months postoperatively.

CONCLUSIONS

The CH and CRF values decreased 1 day after simultaneous cataract surgery with LRIs but soon recovered to preoperative levels, suggesting there were no significant changes in corneal biomechanical factors after 1 day. Corneal thickness may play a role in biomechanical factors even in such eyes.

摘要

目的

确定白内障手术联合角膜缘松解切口(LRIs)后,角膜结构的改变是否会导致角膜生物力学的变化。

地点

日本神奈川县,北里大学眼科。

设计

观察性病例系列。

方法

本研究使用眼反应分析仪对接受白内障手术联合 LRIs 的患者进行了纵向评估,以测量角膜滞后(CH)和角膜阻力因子(CRF)。还评估了这些生物力学参数与超声角膜测厚仪测量的中央角膜厚度(CCT)之间的关系。

结果

术前平均 CH 为 10.0mm Hg±1.2(SD),术后 1 天为 9.0mm Hg±1.6,术后 1 周为 9.7mm Hg±1.4,术后 1 个月为 9.6mm Hg±1.4,术后 3 个月为 10.2mm Hg±1.3。平均 CRF 分别为 10.0mm Hg±1.5、8.9mm Hg±1.6、9.5mm Hg±1.5、9.5mm Hg±1.4 和 9.5mm Hg±1.4。术前与术后 1 天的测量值之间存在显著差异(P=.005,CH;P=.004,CRF)。术后 3 个月,CH 和 CRF 与 CCT 显著相关(r = 0.33,P=.04;r = 0.40,P=.01)。

结论

白内障手术联合 LRIs 后 1 天,CH 和 CRF 值下降,但很快恢复到术前水平,提示术后 1 天角膜生物力学因素无明显变化。角膜厚度即使在这种情况下也可能对生物力学因素起作用。

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