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印度马哈拉施特拉邦双侧先天性及发育性白内障手术的长期预后。米拉杰小儿白内障研究III。

Long term outcomes of bilateral congenital and developmental cataracts operated in Maharashtra, India. Miraj pediatric cataract study III.

作者信息

Gogate Parikshit M, Sahasrabudhe Mohini, Shah Mitali, Patil Shailbala, Kulkarni Anil N, Trivedi Rupal, Bhasa Divya, Tamboli Rahin, Mane Rekha

机构信息

Lions NAB Eye Hospital, Miraj, District Sangli; Dr. Gogate's Eye Clinic; D.Y.Patil Medical College, Pimpri, Pune, Maharashtra, India.

出版信息

Indian J Ophthalmol. 2014 Feb;62(2):186-95. doi: 10.4103/0301-4738.128630.

Abstract

AIM

To study long term outcome of bilateral congenital and developmental cataract surgery.

SUBJECTS

258 pediatric cataract operated eyes of 129 children.

MATERIALS AND METHODS

Children who underwent pediatric cataract surgery in 2004-8 were traced and examined prospectively in 2010-11. Demographic and clinical factors were noted from retrospective chart readings. All children underwent visual acuity estimation and comprehensive ocular examination in a standardized manner. L. V. Prasad Child Vision Function scores (LVP-CVF) were noted for before and after surgery.

STATISTICS

Statistical analysis was done with SPSS version 16 including multi-variate analysis.

RESULTS

Children aged 9.1 years (std dev 4.6, range 7 weeks-15 years) at the time of surgery. 74/129 (57.4%) were boys. The average duration of follow-up was 4.4 years (stddev 1.6, range 3-8 years). 177 (68.6%) eyes had vision <3/60 before surgery, while 109 (42.2%) had best corrected visual acuity (BCVA) >6/18 and 157 (60.9%) had BCVA >6/60 3-8 years after surgery. 48 (37.2%) had binocular stereoacuity <480 sec of arc by TNO test. Visual outcome depended on type of cataract (P = 0.004), type of cataract surgery (P < 0.001), type of intra-ocular lens (P = 0.05), age at surgery (P = 0.004), absence of post-operative uveitis (P = 0.01) and pre-operative vision (P < 0.001), but did not depend on delay (0.612) between diagnosis and surgery. There was a statistically significant improvement for all the 20 questions of the LVP-CVF scale (P < 0.001).

CONCLUSION

Pediatric cataract surgery improved the children's visual acuity, stereo acuity and vision function. Developmental cataract, use of phacoemulsification, older children and those with better pre-operative vision had betterlong-termoutcomes.

摘要

目的

研究双侧先天性及发育性白内障手术的长期疗效。

对象

129名儿童的258只接受小儿白内障手术的眼睛。

材料与方法

对2004年至2008年接受小儿白内障手术的儿童在2010年至2011年进行前瞻性追踪检查。通过回顾病历记录人口统计学和临床因素。所有儿童均以标准化方式进行视力评估和全面的眼部检查。记录手术前后的L.V.普拉萨德儿童视觉功能评分(LVP-CVF)。

统计学方法

使用SPSS 16版软件进行统计学分析,包括多变量分析。

结果

手术时儿童年龄为9.1岁(标准差4.6,范围7周 - 15岁)。74/129(57.4%)为男孩。平均随访时间为4.4年(标准差1.6,范围3 - 8年)。177只(68.6%)眼睛术前视力<3/60,而109只(42.2%)最佳矫正视力(BCVA)>6/18,157只(60.9%)术后3 - 8年BCVA>6/60。48名(37.2%)通过TNO测试双眼立体视锐度<480秒弧度。视觉预后取决于白内障类型(P = 0.004)、白内障手术类型(P < 0.001)、人工晶状体类型(P = 0.05)、手术年龄(P = 0.004)、无术后葡萄膜炎(P = 0.01)及术前视力(P < 0.001),但不取决于诊断与手术之间的间隔时间(0.612)。LVP-CVF量表的所有20个问题均有统计学显著改善(P < 0.001)。

结论

小儿白内障手术改善了儿童的视力、立体视锐度和视觉功能。发育性白内障、使用超声乳化术、年龄较大的儿童以及术前视力较好者长期预后更佳。

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