Bchir Ahlem, Ahmed Slim Ben, Mokni Moncef
Laboratoire d´Anatomie et Cytologie Pathologique, Centre Hospitalier Universitaire Farhat Hached de Sousse, Sousse, Tunisie.
Faculté de Médecine Ibn Jazzar, Sousse, Tunisie.
Pan Afr Med J. 2022 Dec 23;43:206. doi: 10.11604/pamj.2022.43.206.29691. eCollection 2022.
Primary pulmonary salivary gland-type tumors are rare and characterized by a specific clinico-pathological manifestation. They are proximal tumors affecting young subjects and not associated with smoking. For optimal management, it is important to distinguish them from other bronchopulmonary tumors, with which they don´t share either biology or treatment and outcome. We conducted a retrospective study, including all primary malignant salivary gland-type tumors of the lung, over a period of 32 years, from January 1987 to December 2019. We collected data from the medical records of 10 patients: 5 men and 5 women (sex ratio 1). The average age of our patients was 47.4 years. In all cases radiological examinations showed proximally located nodular tumor ranging in size from 1 to 5.8 cm. Histological examination objectified mucoepidermoid carcinoma (6 out of 10 cases). All patients had localized or locally advanced tumors, with the exception of one case of metastatic mucoepidermoid carcinoma. Pulmonary salivary gland-type tumors correspond to a heterogeneous group of tumours. They are not very aggressive but are associated with a high frequency of recurrences and late metastases, requiring long-term monitoring.
原发性肺涎腺型肿瘤罕见,具有特定的临床病理表现。它们是累及年轻患者的近端肿瘤,与吸烟无关。为了进行最佳管理,将它们与其他支气管肺肿瘤区分开来很重要,因为它们在生物学、治疗和预后方面均不相同。我们进行了一项回顾性研究,纳入了1987年1月至2019年12月这32年间所有原发性肺恶性涎腺型肿瘤。我们从10例患者的病历中收集了数据:5名男性和5名女性(性别比为1)。我们患者的平均年龄为47.4岁。所有病例的影像学检查均显示近端有结节状肿瘤,大小从1至5.8厘米不等。组织学检查确诊为黏液表皮样癌(10例中有6例)。除1例转移性黏液表皮样癌外,所有患者均为局限性或局部晚期肿瘤。肺涎腺型肿瘤是一组异质性肿瘤。它们侵袭性不强,但复发和晚期转移的频率较高,需要长期监测。