隐球菌性肋骨骨髓炎作为特发性CD4细胞减少症的主要且唯一症状。
Cryptococcal rib osteomyelitis as primary and only symptom of idiopathic CD4 penia.
作者信息
Legarth Rebecca A, Christensen Merete, Calum Henrik, Katzenstein Terese L, Helweg-Larsen Jannik
机构信息
Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen O, Denmark.
Department of Thoracic Surgery, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen O, Denmark.
出版信息
Med Mycol Case Rep. 2014 Feb 25;4:16-8. doi: 10.1016/j.mmcr.2014.02.002. eCollection 2014 Apr.
Abstract
A 59-year old man with idiopathic CD4 lymphopenia presented with extensive disseminated Cryptococcus neoformans infection including a large rib cryptoccocoma, vertebral spondylitis and pleural empyema. Complete resection of the affected part of the rib was necessary after failure of initial antifungal treatment. The vertebral spondylitis has been successfully managed at 3 years of follow-up by continuous itraconazole treatment and regular MRI combined with leucocyte scintigraphy assessment.
摘要
一名患有特发性CD4淋巴细胞减少症的59岁男性出现广泛播散性新型隐球菌感染，包括巨大肋骨隐球菌瘤、椎体脊柱炎和胸膜脓胸。初始抗真菌治疗失败后，有必要对肋骨的受累部分进行完整切除。在3年的随访中，通过持续伊曲康唑治疗、定期MRI检查并结合白细胞闪烁扫描评估，椎体脊柱炎得到了成功控制。
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