免疫功能正常患者腰椎孤立性隐球菌病：一例报告及文献复习
Isolated cryptococcosis of a lumbar vertebra in an immunocompetent patient: A case report and literature review.
作者信息
Jia Zhongxiong, Tang Min, Zhang Xiaojun, Xin Xiaojuan, Jiang Wei, Hao Jie
机构信息
Department of Orthopedics, The Second People's Hospital of Yibin, Yibin, China.
Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
出版信息
Front Surg. 2023 Jan 6;9:1079732. doi: 10.3389/fsurg.2022.1079732. eCollection 2022.
BACKGROUND
, a kind of fungus, can be found in soil, decayed wood, and avian excreta. Immunocompromised patients are prone to infection caused by , and the lungs and central nervous system are the main target organs. Cryptococcosis rarely occurs in the lumbar vertebra or in immunocompetent patients.
CASE PRESENTATION
A 40-year-old adult male with isolated lumbar vertebra cryptococcosis at the L4 vertebra underwent successful lesion removal surgery performed the posterior approach and postoperative administration of an antifungal agent. At the 12-month follow-up, the patient's pain was relieved, and his motor function had improved. Isolated vertebrae infection is a rare infectious disease.
CONCLUSIONS
A needle biopsy can confirm the diagnosis of infection. When patients present with unbearable symptoms of nerve compression, posterior depuration combined with postoperative antifungal agents is a good option.
背景
新型隐球菌是一种真菌，可在土壤、腐朽木材和鸟类排泄物中发现。免疫功能低下的患者容易受到新型隐球菌感染，肺部和中枢神经系统是主要靶器官。新型隐球菌病很少发生在腰椎或免疫功能正常的患者中。
病例介绍
一名40岁成年男性，L4椎体孤立性腰椎新型隐球菌病，采用后路入路成功进行了病变切除手术，并术后给予抗真菌药物治疗。在12个月的随访中，患者疼痛缓解，运动功能有所改善。孤立性椎体感染是一种罕见的传染病。
结论
针吸活检可确诊新型隐球菌感染。当患者出现难以忍受的神经压迫症状时，后路清创术联合术后抗真菌药物是一个不错的选择。
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