Acdegroot Publishing, Schipslootweg 5, 8351 HV, Wapserveen, The Netherlands.
Contact Dermatitis. 2014 Apr;70(4):193-204. doi: 10.1111/cod.12205.
Octocrylene is an ultraviolet (UV)B and UVAII absorber that was introduced some 15 years ago, and is now widely used in sunscreen agents and skin care cosmetics. Since 2003, several studies, notably from France, Belgium, Spain, and Italy, have reported an increasing number of patients with photocontact allergy to octocrylene. This reaction is seen mainly in adult patients who have previously used topical products containing the non-steroidal anti-inflammatory drug ketoprofen. Photosensitization to ketoprofen leads, in many cases, to photocontact allergy to octocrylene; the mechanism of this reaction is unknown. Contact allergy to octocrylene also occurs, but is far less frequent, and is seen, in most cases, in children, resulting from the use of octocrylene-containing sunscreen products. In this article, (photo)contact allergy to octocrylene is fully reviewed.
辛氧苯酮是一种紫外线 (UV)B 和 UVAII 吸收剂，约 15 年前被引入市场，目前广泛应用于防晒霜和护肤品中。自 2003 年以来，法国、比利时、西班牙和意大利等国的多项研究报告称，越来越多的光接触过敏患者对辛氧苯酮过敏。这种反应主要见于曾使用含有非甾体抗炎药酮洛芬的局部产品的成年患者。酮洛芬光敏作用会导致光接触过敏辛氧苯酮，其反应机制尚不清楚。辛氧苯酮接触过敏也会发生，但频率要低得多，大多数情况下发生在使用含辛氧苯酮的防晒霜产品的儿童中。本文全面回顾了辛氧苯酮的（光）接触过敏。
