拉曼光谱法提供了一种用于在体内确定妊娠宫颈生化成分的非侵入性方法。
Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo.
作者信息
O'Brien Christine M, Vargis Elizabeth, Paria Bibhash C, Bennett Kelly A, Mahadevan-Jansen Anita, Reese Jeff
机构信息
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
出版信息
Acta Paediatr. 2014 Jul;103(7):715-21. doi: 10.1111/apa.12630. Epub 2014 Apr 17.
Abstract
UNLABELLED
The molecular changes that occur with cervical remodelling during pregnancy are not completely understood. This study reviews Raman spectroscopy, an optical technique for detecting changes in the pregnant cervix, and reports preliminary studies on cervical remodelling in mice that suggest that the technique provides advantages over other methods.
CONCLUSION
Raman spectroscopy is sensitive to biochemical changes in the pregnant cervix and has high potential as a tool for detecting premature cervical remodelling in pregnant women.
摘要
未标注
孕期宫颈重塑过程中发生的分子变化尚未完全明确。本研究回顾了拉曼光谱法（一种用于检测妊娠宫颈变化的光学技术），并报告了对小鼠宫颈重塑的初步研究，表明该技术比其他方法具有优势。
结论
拉曼光谱法对妊娠宫颈的生化变化敏感，作为检测孕妇宫颈过早重塑的工具具有很大潜力。
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