Amaral Lígia Menezes do, Moratelli Lucas, Palma Pamella Valente, Leite Isabel Cristina Gonçalves
Division of Pulmonology, Department of Internal Medicine, Federal University of Juiz de Fora , Juiz de Fora , Brazil .
J Asthma. 2014 Aug;51(6):660-6. doi: 10.3109/02770903.2014.903964. Epub 2014 Apr 7.
Asthma is the most common chronic disease among adolescents. This study assessed the quality of life (QOL) related to health in adolescents with asthma and its determining factors (demographic, socioeconomic, and clinical). We also separately evaluated each of the parameters that comprised the asthma control classification.
This was an observational, cross-sectional study of 114 adolescents who had doctor-diagnosed asthma. QOL was assessed using a version of the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) that was adapted and validated for Brazil, and higher scores indicated a better QOL. The level of asthma control was assessed using the rating system proposed by the Global Initiative for Asthma, and sociodemographic factors were evaluated.
When the averages of the PAQLQ domains and overall scores were compared to the potentially explanatory variables, significantly lower average PAQLQ scores were obtained for individuals with an inadequate level of asthma control (p < 0.001). Of the control components, daytime symptoms, nighttime symptoms, and limited physical activity were related to QOL. However, the use of the β2 agonist and the peak flow functional parameter were not related to QOL.
The level of asthma control was related to QOL, but this association manifested mainly in the subjective control domains, such as nighttime and daytime symptoms and physical activity limitations. The objective domain for control classification, represented by pulmonary function, was not an independent predictor or determinant of the QOL of adolescent asthma patients.
哮喘是青少年中最常见的慢性疾病。本研究评估了哮喘青少年的健康相关生活质量(QOL)及其决定因素(人口统计学、社会经济和临床因素)。我们还分别评估了构成哮喘控制分类的每个参数。
这是一项对114名经医生诊断为哮喘的青少年进行的观察性横断面研究。使用针对巴西改编并验证的《儿童哮喘生活质量问卷》(PAQLQ)版本评估生活质量,得分越高表明生活质量越好。使用全球哮喘防治创议提出的评分系统评估哮喘控制水平,并评估社会人口统计学因素。
将PAQLQ各领域和总分的平均值与潜在解释变量进行比较时,哮喘控制水平不足的个体获得的PAQLQ平均得分显著更低(p < 0.001)。在控制因素中,日间症状、夜间症状和身体活动受限与生活质量相关。然而,β2激动剂的使用和峰值流量功能参数与生活质量无关。
哮喘控制水平与生活质量相关,但这种关联主要体现在主观控制领域,如夜间和日间症状以及身体活动受限。以肺功能为代表的控制分类客观领域并非青少年哮喘患者生活质量的独立预测因素或决定因素。