Xu Kuo, Wang Penglong, Wang Lin, Liu Congmin, Xu Shixun, Cheng Yatao, Wang Yanhui, Li Qiang, Lei Haimin
School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, P. R. China, (phone: +86-1084738640; fax: +86-1082686933).
Chem Biodivers. 2014 Mar;11(3):341-63. doi: 10.1002/cbdv.201200173.
The extracts and phytochemicals of the genus Rubia have drawn much attention due to their potent effects; among them, naphthoquinone and cyclopeptide derivatives, with significant biological activities, have great potential to be developed to new drugs. This review updates and compiles a total of 142 quinone derivatives including anthraquinone and naphthoquinone derivatives, occuring in twelve Rubia species. These compounds were listed together with their sources, melting points, bioactivities, as well as 112 corresponding references. Furthermore, the structureactivity relationships of these quinone derivatives were discussed.
茜草属植物的提取物和植物化学物质因其强大的功效而备受关注；其中，具有显著生物活性的萘醌和环肽衍生物具有开发成新药的巨大潜力。本综述更新并汇编了总共142种醌类衍生物，包括蒽醌和萘醌衍生物，它们存在于12种茜草属植物中。这些化合物与其来源、熔点、生物活性以及112篇相应参考文献一起列出。此外，还讨论了这些醌类衍生物的构效关系。
