Department of Orthopedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Yanchang Middle Road, Shanghai 200072, China.
Diagn Pathol. 2014 Mar 18;9:60. doi: 10.1186/1746-1596-9-60.
Patellofemoral pathology is common, and patellofemoral dislocation mainly affects adolescents and young adults. We conducted a meta-analysis exclusively of RCTs to compare the clinical outcomes of patellar dislocation patients managed operatively versus non-operatively.
After systematic review of electronic databases and websites, a total of 7 RCTs reporting data on 402 subjects were included. The methodological quality of the literature was assessed using the PEDro critical appraisal tool. Mean differences (MDs) and risk ratio (RR) were calculated for the pooled effects. Heterogeneity was assessed using the I2 test.
Data synthesis showed a lower rate of recurrent patellar dislocation post-treatment in patients managed operatively compared to non-operatively (P=0.01).
The results suggest a difference in outcomes between the treatment strategies. However the limited number of studies and high risk of inherent bias indicate that future studies involving more patients in better-designed randomized controlled trials will be required.
The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/8011948721221355.
髌股关节疾病较为常见，髌股关节脱位主要影响青少年和年轻成年人。我们专门进行了一项荟萃分析，比较了手术与非手术治疗髌股关节脱位患者的临床结果。
系统地回顾了电子数据库和网站后，共纳入了 7 项 RCT，共纳入了 402 例患者。使用 PEDro Critical Appraisal Tool 评估文献的方法学质量。采用 MD 和 RR 计算汇总效应。采用 I2 检验评估异质性。
数据综合表明，与非手术治疗相比，手术治疗后的复发性髌股关节脱位率较低（P=0.01）。
结果表明治疗策略之间存在结果差异。但是，研究数量有限且存在固有偏倚的高风险表明，需要未来进行更多患者参与的更好设计的随机对照试验研究。
