Bhattarai Tirtha, Bhattacharya Koushik, Chaudhuri Prasenjit, Sengupta Pallav
Department of Community Health, Everest Nursing College, Nepal, Pincode 44600, India.
Department of Physiology, Vidyasagar College for Women, University of Calcutta, Kolkata, Pincode 700006, West Bengal, India.
Malays J Med Sci. 2014 Jan;21(1):58-61.
The quality of life for women after menopause is one of the key health issues today, and osteoporosis is a silently progressing metabolic bone disease widely prevalent in post-menopausal women in India. Rapid bone loss occurs in post-menopausal women due to hormonal factors that lead to an increased risk of fractures. Thus, the present study was undertaken to observe the serum calcium and alkaline phosphatase (ALP) levels in post-menopausal women as these substances are biochemical markers of bone metabolism. In this small-scale cross-sectional study, 100 samples were taken. Of these, 50 were taken from post-menopausal women (experimental group) and 50 were taken from pre-menopausal women (control group). Serum calcium and serum ALP were measured in the blood samples of both groups. The findings demonstrated that the serum calcium level was significantly lower in the post-menopausal group than in the pre-menopausal group, while the ALP level was slightly higher. Therefore, an increase in bone turnover accelerates bone mass reduction in post-menopausal women, whereas a decrease in bone turnover is associated with the preservation of bone mass.
绝经后女性的生活质量是当今关键的健康问题之一，而骨质疏松症是一种在印度绝经后女性中广泛流行的、悄然进展的代谢性骨病。绝经后女性由于激素因素会出现快速骨质流失，导致骨折风险增加。因此，本研究旨在观察绝经后女性的血清钙和碱性磷酸酶（ALP）水平，因为这些物质是骨代谢的生化标志物。在这项小规模横断面研究中，采集了100份样本。其中，50份取自绝经后女性（实验组），50份取自绝经前女性（对照组）。对两组血液样本中的血清钙和血清ALP进行了测量。研究结果表明，绝经后组的血清钙水平显著低于绝经前组，而ALP水平略高。因此，骨转换增加会加速绝经后女性的骨质减少，而骨转换降低与骨质保留有关。
