Department of Psychological and Brain Sciences, Indiana University, , Bloomington, IN 47405-7007, USA.
Biol Lett. 2014 Mar 19;10(3):20140064. doi: 10.1098/rsbl.2014.0064. Print 2014 Mar.
Source memory represents the origin (source) of information. Recently, we proposed that rats (Rattus norvegicus) remember the source of information. However, an alternative to source memory is the possibility that rats selectively encoded some, but not all, information rather than retrieving an episodic memory. We directly tested this 'encoding failure' hypothesis. Here, we show that rats remember the source of information, under conditions that cannot be attributed to encoding failure. Moreover, source memory lasted at least seven days but was no longer present 14 days after studying. Our findings suggest that long-lasting source memory may be modelled in non-humans. Our model should facilitate attempts to elucidate the biological underpinnings of source memory impairments in human memory disorders such as Alzheimer's disease.
源记忆代表信息的来源（源）。最近，我们提出大鼠（Rattus norvegicus）能够记住信息的来源。然而，源记忆的另一种解释是，大鼠选择性地编码了一些信息，但不是全部，而不是检索情景记忆。我们直接检验了这个“编码失败”假说。在这里，我们表明，在不能归因于编码失败的条件下，大鼠能够记住信息的来源。此外，源记忆至少持续七天，但在学习后 14 天不再存在。我们的发现表明，非人类动物可以建立持久的源记忆模型。我们的模型应该有助于尝试阐明人类记忆障碍（如阿尔茨海默病）中源记忆损伤的生物学基础。
