Man G S, Mologhianu G
"Carol Davila" University of Medicine and Pharmacy, Gastroenterology Department, Emergency University Hospital, Bucharest.
"Carol Davila" University of Medicine and Pharmacy, Department of Rehabilitation Medicine, 3rd Rehabilitation Clinic of National Institute of Rehabilitation, Physical Medicine and Balneology, Bucharest.
J Med Life. 2014 Mar 15;7(1):37-41. Epub 2014 Mar 25.
Osteoarthritis is the most common joint disorder and a major cause of disability with a major socio-economic impact. In these circumstances is very important to understand its pathogenesis. Although previous research focused primarily on changes in the articular cartilage, more recent studies have highlighted the importance of the subchondral bone, synovium, menisci, ligaments, periarticular muscles and nerves. Now osteoarthritis is viewed as a multifactorial disease affecting the whole joint.
骨关节炎是最常见的关节疾病，也是导致残疾的主要原因，具有重大的社会经济影响。在这种情况下，了解其发病机制非常重要。尽管先前的研究主要集中在关节软骨的变化上，但最近的研究强调了软骨下骨、滑膜、半月板、韧带、关节周围肌肉和神经的重要性。现在，骨关节炎被视为一种影响整个关节的多因素疾病。
