School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Biosens Bioelectron. 2014 Aug 15;58:237-41. doi: 10.1016/j.bios.2014.02.081. Epub 2014 Mar 12.
A novel electrochemical sensor using the molecularly imprinted (MIP) oxygen-containing polypyrrole (PPy) decorated carbon nanotubes (CNTs) composite was proposed for in vivo detection of dopamine (DA). The prepared sensor exhibits a remarkable sensitivity of (16.18μA/μM) with a linear range of 5.0×10(-11)-5.0×10(-6)M and limit of detection as low as 1.0×10(-11)M in the detection of DA, which might be due to the plenty cavities for binding DA through π-π stacking between aromatic rings and hydrogen bonds between amino groups of DA and oxygen-containing groups of the novel PPy.
一种新型电化学传感器，使用分子印迹（MIP）含氧聚吡咯（PPy）修饰的碳纳米管（CNTs）复合材料，用于体内多巴胺（DA）的检测。所制备的传感器在检测 DA 时表现出显著的灵敏度（16.18μA/μM），线性范围为 5.0×10(-11)-5.0×10(-6)M，检测限低至 1.0×10(-11)M，这可能是由于通过芳香环之间的π-π堆积和 DA 的氨基与新型 PPy 的含氧基团之间的氢键，存在大量结合 DA 的空腔。
