Souza Francisley Á, Queiroz Thallita P, Sonoda Celso K, Okamoto Roberta, Margonar Rogério, Guastaldi Antônio C, Nishioka Renato S, Garcia Júnior Idelmo R
Department of Surgery and General Clinic, Araçatuba of Dental School, Univ Estadual Paulista Júlio de Mesquita Filho - UNESP, Araçatuba, Brazil.
J Biomed Mater Res B Appl Biomater. 2014 Nov;102(8):1677-88. doi: 10.1002/jbm.b.33139. Epub 2014 Mar 25.
Biologic behavior of the bone tissue around implants with four different surfaces was evaluated. The surfaces were: modified by laser (LS); modified by laser with sodium silicate deposition (SS); and commercially available surfaces modified by acid etching (AS) and machined surface (MS). Topographic characterization of the surfaces was performed by scanning electron microscopy (SEM)- energy dispersive X-ray spectrometry (EDX) before experimental surgery. Thirty rabbits received 60 implants in their right and left tibias, 1 implant of each surface being placed in each tibia. The analyzed periods were 4, 8, and 12 weeks postoperatively. Histometric analysis was performed evaluating bone interface contact (BIC) and bone area (BA). The results obtained were submitted to the analysis of variance and the Tukey t-test. The elemental mapping was evaluated by means of SEM at 4 weeks postoperatively. The topographic characterization showed differences between the analyzed surfaces. Generally, the BIC and BA of LS and SS implants were statistically higher than those of AS and MS in most of the analyzed periods. Elemental mapping showed high peaks of calcium and phosphorous in all groups. Based on the present methodology, it may be concluded that experimental modifications LS and SS accelerated the stages of the bone tissue repair process around the implants, providing the highest degree of osseointegration.
评估了具有四种不同表面的种植体周围骨组织的生物学行为。这些表面分别为：经激光改性（LS）；经激光改性并沉积硅酸钠（SS）；市售的经酸蚀改性表面（AS）和机械加工表面（MS）。在实验手术前，通过扫描电子显微镜（SEM）-能量色散X射线光谱法（EDX）对表面进行形貌表征。30只兔子在其左右胫骨中植入60枚种植体，每只胫骨中植入每种表面的1枚种植体。分析的时间段为术后4、8和12周。进行组织计量学分析，评估骨界面接触（BIC）和骨面积（BA）。将获得的结果进行方差分析和Tukey t检验。术后4周通过SEM评估元素映射。形貌表征显示分析的表面之间存在差异。一般来说，在大多数分析时间段内，LS和SS种植体的BIC和BA在统计学上高于AS和MS种植体。元素映射显示所有组中钙和磷的峰值较高。基于目前的方法，可以得出结论，实验性改性LS和SS加速了种植体周围骨组织修复过程的阶段，提供了最高程度的骨整合。
