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一种源自含蒽双烯大环化合物的开启型荧光铁(Ⅲ)传感器及其细胞内成像应用

A turn-on fluorescent Fe(3+) sensor derived from an anthracene-bearing bisdiene macrocycle and its intracellular imaging application.

作者信息

Qiu Lin, Zhu Chengcheng, Chen Huachao, Hu Ming, He Weijiang, Guo Zijian

机构信息

State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.

出版信息

Chem Commun (Camb). 2014 May 7;50(35):4631-4. doi: 10.1039/c3cc49482a.

Abstract

Integrating N(2)-hydroxyethyldiethylenetriamine with anthracene gives a [2+2] macrocycle fluorescent sensor. This sensor displays an instant/reversible turn-on response specific to Fe(3+), which allows facile visualization of the Fe(3+)/Fe(2+) transition and intracellular Fe(3+) imaging.

摘要

将N(2)-羟乙基二亚乙基三胺与蒽整合得到一种[2+2]大环荧光传感器。该传感器对Fe(3+)呈现即时/可逆的开启响应,能够轻松实现Fe(3+)/Fe(2+)转变的可视化以及细胞内Fe(3+)成像。

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