Department of Haematology, Oncology and Tumor Immunology, University Medical Center Charité, Augustenburger Platz 1, 13353, Berlin, Germany,
Support Care Cancer. 2014 Aug;22(8):2241-9. doi: 10.1007/s00520-014-2181-8. Epub 2014 Mar 27.
Cancer-related fatigue is a multidimensional symptom with an underestimated prevalence and severity in cancer patients. The aim of the study was to evaluate the effect of dance as a holistic sportive activity in cancer patients under active anticancer treatment with fatigue as endpoint.
Forty patients under active anticancer treatment (adjuvant (25), palliative (11) or neoadjuvant (4)) with moderate or severe fatigue (≥ 4 on the visual analogue scale) were investigated in two groups for severity of fatigue (visual analogue scale, Functional Assessment of Chronic Illness Therapy: Fatigue questionnaire), quality of life (European Organization for Research and Treatment of Cancer, Quality of Life Questionnaire) and physical performance (6-minute walk test) before and after the study period--group A (n = 20): intervention (10 dance classes in 5 weeks in addition to counselling) and group B (n = 20): control (no dance, standard of care, counselling).
We found significant improvements for cancer-related fatigue in the intervention group (baseline mean ± SD 5.95 ± 1.701, end-of-study mean 3.8 ± 1.542, p = 0.001, reduction of 36 %) compared to the control group (baseline mean 4.95 ± 0.999, end-of-study mean unchanged at 5.0 ± 1.556, p = 0.887); as well as for emotional and social functioning scales and physical performance (p < 0.05).
Dance might be an appropriate, effective approach for treatment of cancer-related fatigue.
癌症相关性疲劳是一种具有多维度的症状，在癌症患者中其发生率和严重程度被低估。本研究旨在评估舞蹈作为一种整体运动性活动对正在接受癌症治疗（辅助治疗 25 例，姑息治疗 11 例，新辅助治疗 4 例）且伴有疲劳的癌症患者的影响，疲劳是本研究的终点。
40 名正在接受癌症治疗（辅助治疗 25 例，姑息治疗 11 例，新辅助治疗 4 例）且疲劳程度为中度或重度（视觉模拟量表≥4）的患者被分为两组，分别为 A 组（n=20）和 B 组（n=20）。A 组（干预组）在研究期间接受了 10 节舞蹈课程（5 周）和咨询，B 组（对照组）未接受舞蹈治疗，仅接受标准护理和咨询。在研究前后，我们评估了两组患者的疲劳严重程度（视觉模拟量表、慢性病治疗功能评估-疲劳问卷）、生活质量（欧洲癌症研究与治疗组织生活质量问卷）和身体表现（6 分钟步行试验）。
与对照组相比，干预组的癌症相关性疲劳显著改善（基线平均±SD 5.95±1.701，研究结束时平均 3.8±1.542，p=0.001，降低了 36%）；同时，干预组的情感和社会功能量表以及身体表现也得到了改善（p<0.05）。
舞蹈可能是治疗癌症相关性疲劳的一种合适且有效的方法。
