尿液气球菌的体外抗菌药敏性。
In vitro antimicrobial susceptibility of Aerococcus urinae.
作者信息
Humphries Romney M, Hindler Janet A
机构信息
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
出版信息
J Clin Microbiol. 2014 Jun;52(6):2177-80. doi: 10.1128/JCM.00418-14. Epub 2014 Mar 26.
Abstract
Aerococcus urinae may cause urinary tract infections, bacteremia, and endocarditis. No standardized susceptibility test methods or interpretive criteria have been proposed for this organism. This study reports the MIC results for 128 A. urinae isolates tested by broth microdilution. The isolates had low MICs to amoxicillin, cefotaxime, ceftriaxone, doxycycline, linezolid, meropenem, penicillin, rifampin, tetracycline, trimethoprim-sulfamethoxazole, and vancomycin. However, 55% of the isolates had MICs to clindamycin of >0.25 μg/ml, 44% had MICs to erythromycin of >0.25 μg/ml, and 16% had MICs to levofloxacin of >2 μg/ml.
摘要
尿液气球菌可能导致尿路感染、菌血症和心内膜炎。目前尚未针对该菌提出标准化的药敏试验方法或解释标准。本研究报告了采用肉汤微量稀释法对128株尿液气球菌分离株进行检测的MIC结果。这些分离株对阿莫西林、头孢噻肟、头孢曲松、多西环素、利奈唑胺、美罗培南、青霉素、利福平、四环素、甲氧苄啶-磺胺甲恶唑和万古霉素的MIC值较低。然而，55%的分离株对克林霉素的MIC值>0.25μg/ml，44%的分离株对红霉素的MIC值>0.25μg/ml，16%的分离株对左氧氟沙星的MIC值>2μg/ml。
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