重叠功能性消化不良或消化性溃疡病与胃食管反流病患者的危险因素和生活质量。
The risk factors and quality of life in patients with overlapping functional dyspepsia or peptic ulcer disease with gastroesophageal reflux disease.
机构信息
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan. ; Department of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan. ; Department of Medicine, Yang Ming University, Taipei, Taiwan.
出版信息
Gut Liver. 2014 Mar;8(2):160-4. doi: 10.5009/gnl.2014.8.2.160. Epub 2013 Nov 5.
BACKGROUND/AIMS: Gastroesophageal reflux disease (GERD), functional dyspepsia (FD), and peptic ulcer disease (PUD) impact the daily lives of affected individuals. The aim of this study was to compare the risk factors and impacts on life quality of overlapping FD or PUD in patients with GERD.
METHODS
Data from patients diagnosed with GERD were collected between January and November 2009. FD was defined using the Rome III diagnostic criteria. The overlapping GERD-FD or GERD-PUD groups were classified as concomitant GERD and FD or peptic ulcers. The characteristics of these individuals were analyzed.
RESULTS
There were 63, 48, and 60 patients in the GERD only, overlapping GERD-FD, and overlapping GERD-PUD groups, respectively. Significantly younger age, female gender, lower body weight and body mass index, and higher rates of tea consumption were noted in the GERD-FD group. Patients in the GERD-FD group exhibited the lowest quality of life scores, both with respect to physical and mental health, on the Short Form 36 domains.
CONCLUSIONS
Patients with concomitant GERD and FD were more likely to be younger and female. Overlapping GERD and FD had the worst impact on the quality of life of the affected individuals.
背景/目的：胃食管反流病（GERD）、功能性消化不良（FD）和消化性溃疡病（PUD）影响患者的日常生活。本研究旨在比较 GERD 重叠 FD 或 PUD 的患者的危险因素和对生活质量的影响。
方法
2009 年 1 月至 11 月间收集了诊断为 GERD 的患者的数据。FD 采用 Rome III 诊断标准定义。重叠 GERD-FD 或 GERD-PUD 组被归类为同时存在 GERD 和 FD 或消化性溃疡。分析了这些患者的特征。
结果
GERD 组、重叠 GERD-FD 组和重叠 GERD-PUD 组分别有 63、48 和 60 例患者。GERD-FD 组年龄显著较小，女性比例、体重和体重指数较低，饮茶率较高。在 Short Form 36 领域，GERD-FD 组的患者生理和心理健康评分最低。
结论
同时患有 GERD 和 FD 的患者更年轻、更女性化。重叠 GERD 和 FD 对患者的生活质量影响最严重。
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