Department of Chemistry and Biochemistry, Jackson State University, 1400 J.R. Lynch St, Jackson, MS, USA.
Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, 3900 NCTR Road, Jefferson, AR, USA.
J Food Drug Anal. 2014 Mar;22(1):3-17. doi: 10.1016/j.jfda.2014.01.001. Epub 2014 Jan 31.
Cancer is the second leading cause of death in the USA according to the American Cancer Society. In the past 5 years, "theranostic nanomedicine", for both therapeutics and imaging, has shown to be "the right drug for the right patient at the right moment" to manage deadly cancers. This review article presents an overview of recent developments, mainly from the authors' laboratories, along with potential medical applications for theranostic nanomedicine including basic concepts and critical properties. Finally, we outline the future research direction and possible challenges for theranostic nanomedicine research.
根据美国癌症协会的数据，癌症是美国的第二大致死原因。在过去的 5 年中，“治疗诊断纳米医学”在治疗和成像方面都表现出“在正确的时刻为正确的患者提供正确的药物”，以治疗致命癌症。本文综述了近期的研究进展，主要来自作者实验室，并介绍了治疗诊断纳米医学的潜在医学应用，包括基本概念和关键特性。最后，我们概述了治疗诊断纳米医学研究的未来研究方向和可能面临的挑战。
