Department of Biology, Jackson State University, Jackson, MS 39217, USA.
Environmental Science Ph.D. Program, Jackson State University, Jackson, MS 39217, USA.
J Food Drug Anal. 2014 Mar;22(1):128-146. doi: 10.1016/j.jfda.2014.01.011. Epub 2014 Feb 4.
In this report, we critically reviewed selected intrinsic physicochemical properties of engineered nanomaterials (ENMs) and their role in the interaction of the ENMs with the immediate surroundings in representative aquatic environments. The behavior of ENMs with respect to dynamic microenvironments at the nano-bio-eco interface level, and the resulting impact on their toxicity, fate, and exposure potential are elaborated. Based on this literature review, we conclude that a holistic approach is urgently needed to fulfill our knowledge gap regarding the safety of discharged ENMs. This comparative approach affords the capability to recognize and understand the potential hazards of ENMs and their toxicity mechanisms, and ultimately to establish a quantitative and reliable system to predict such outcomes.
在本报告中，我们批判性地回顾了工程纳米材料（ENMs）的选定固有物理化学性质及其在代表性水生环境中与周围环境相互作用的作用。阐述了纳米-生物-生态界面水平上 ENMs 对动态微环境的行为及其对毒性、命运和暴露潜力的影响。基于文献综述，我们得出结论，迫切需要采用整体方法来弥补我们在排放的 ENMs 安全性方面的知识差距。这种比较方法能够识别和理解 ENMs 的潜在危害及其毒性机制，并最终建立一个定量和可靠的系统来预测这些结果。
