Erdman S E, Poutahidis T
Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA Faculty of Veterinary Medicine, Laboratory of Pathology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Benef Microbes. 2014 Jun 1;5(2):109-19. doi: 10.3920/BM2013.0042.
Radiant skin and hair are universal indicators of good health. It was recently shown that feeding of probiotic bacteria to aged mice rapidly induced youthful vitality characterised by thick lustrous skin and hair, and enhanced reproductive fitness, not seen in untreated controls. Probiotic-treated animals displayed integrated immune and hypothalamic-pituitary outputs that were isolated mechanistically to microbe-induced anti-inflammatory interleukin-10 and neuropeptide hormone oxytocin. In this way, probiotic microbes interface with mammalian physiological underpinnings to impart superb physical and reproductive fitness displayed as radiant and resilient skin and mucosae, unveiling novel strategies for integumentary health.
皮肤光泽和头发亮丽是身体健康的普遍指标。最近的研究表明，给老年小鼠喂食益生菌能迅速诱导出年轻活力，其特征为皮肤厚实有光泽、毛发浓密，还能提高生殖健康水平，而未处理的对照组则未出现这些情况。经益生菌处理的动物表现出整合的免疫和下丘脑 - 垂体输出，从机制上看，这与微生物诱导的抗炎白细胞介素 -10 和神经肽激素催产素有关。通过这种方式，益生菌微生物与哺乳动物的生理基础相互作用，赋予其卓越的身体和生殖健康，表现为皮肤和黏膜有光泽且有弹性，为皮肤健康揭示了新策略。
