Kang Minki, Lee Dong-Min, Hyun Inah, Rubab Najaf, Kim So-Hee, Kim Sang-Woo
School of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Department of Materials Science and Engineering, Center for Human-oriented Triboelectric Energy Harvesting, Yonsei University, Seoul 03722, Republic of Korea.
Chem Rev. 2023 Oct 11;123(19):11559-11618. doi: 10.1021/acs.chemrev.3c00301. Epub 2023 Sep 27.
With the growing demand for next-generation health care, the integration of electronic components into implantable medical devices (IMDs) has become a vital factor in achieving sophisticated healthcare functionalities such as electrophysiological monitoring and electroceuticals worldwide. However, these devices confront technological challenges concerning a noninvasive power supply and biosafe device removal. Addressing these challenges is crucial to ensure continuous operation and patient comfort and minimize the physical and economic burden on the patient and the healthcare system. This Review highlights the promising capabilities of bioresorbable triboelectric nanogenerators (B-TENGs) as temporary self-clearing power sources and self-powered IMDs. First, we present an overview of and progress in bioresorbable triboelectric energy harvesting devices, focusing on their working principles, materials development, and biodegradation mechanisms. Next, we examine the current state of on-demand transient implants and their biomedical applications. Finally, we address the current challenges and future perspectives of B-TENGs, aimed at expanding their technological scope and developing innovative solutions. This Review discusses advancements in materials science, chemistry, and microfabrication that can advance the scope of energy solutions available for IMDs. These innovations can potentially change the current health paradigm, contribute to enhanced longevity, and reshape the healthcare landscape soon.
随着对下一代医疗保健需求的不断增长，将电子元件集成到可植入医疗设备（IMD）中已成为在全球范围内实现复杂医疗功能（如电生理监测和电治疗）的关键因素。然而，这些设备面临着与非侵入式电源供应和生物安全设备移除相关的技术挑战。解决这些挑战对于确保设备持续运行、患者舒适度以及最小化患者和医疗系统的身体和经济负担至关重要。本综述重点介绍了生物可吸收摩擦纳米发电机（B-TENG）作为临时自清除电源和自供电IMD的潜在能力。首先，我们概述了生物可吸收摩擦能量收集设备及其进展，重点关注其工作原理、材料开发和生物降解机制。接下来，我们研究了按需瞬态植入物的现状及其生物医学应用。最后，我们探讨了B-TENG当前面临的挑战和未来前景，旨在扩大其技术范围并开发创新解决方案。本综述讨论了材料科学、化学和微制造方面的进展，这些进展可以拓展可用于IMD的能量解决方案的范围。这些创新有可能改变当前的健康模式，有助于延长寿命，并在不久后重塑医疗保健格局。
