精神障碍：从诊断到治疗。
Psychiatric disorders: diagnosis to therapy.
机构信息
Departments of Psychiatry and Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA; VA National Center for PTSD, VA Connecticut Healthcare System, West Haven, CT 06516, USA.
Department of Psychiatry and Langley Porter Psychiatric Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
出版信息
Cell. 2014 Mar 27;157(1):201-14. doi: 10.1016/j.cell.2014.02.042.
Abstract
Recent findings in a range of scientific disciplines are challenging the conventional wisdom regarding the etiology, classification, and treatment of psychiatric disorders. This Review focuses on the current state of the psychiatric diagnostic nosology and recent progress in three areas: genomics, neuroimaging, and therapeutics development. The accelerating pace of novel and unexpected findings is transforming the understanding of mental illness and represents a hopeful sign that the approaches and models that have sustained the field for the past 40 years are yielding to a flood of new data and presaging the emergence of a new and more powerful scientific paradigm.
摘要
最近在一系列科学领域的发现正在挑战有关精神障碍的病因、分类和治疗的传统观念。本综述重点介绍了精神障碍诊断分类学的现状以及三个领域的最新进展：基因组学、神经影像学和治疗方法的开发。新颖和意外发现的加速步伐正在改变对精神疾病的理解，这是一个充满希望的迹象，表明过去 40 年来支撑该领域的方法和模型正在让位于大量新数据，并预示着一个新的、更强大的科学范式的出现。
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