Ye Shaodong, Pang Lin, Wang Xiaochun, Liu Zhongfu
National Center for AIDS/STD Control and Prevention, China Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, 102206, People's Republic of China,
Curr HIV/AIDS Rep. 2014 Jun;11(2):128-33. doi: 10.1007/s11904-014-0206-z.
We sought to profile the epidemiological implication of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) co-infection from South and Southeast Asia by reviewing original studies reporting prevalence of HIV-HCV co-infection and their risk factors. Thirteen papers cited in the PubMed database and published in 2012 and 2013 were reviewed. The overall HCV co-infection prevalence ranged broadly from 1.2 % to 98.5 % among HIV-positive people in South and Southeast Asia. Among HCV seropositive blood donors in Nepal, 5.75 % had HIV co-infection. Injecting drug use (IDU) was one of the key risk factors of co-infection, with HCV infection reaching 89.8 % and 98.5 % among HIV-positive injecting drug users in Vietnam. The most recent data from South and Southeast Asia suggest the urgency of implementation of comprehensive prevention and control strategies of HIV-HCV co-infection.
我们旨在通过回顾报告人类免疫缺陷病毒(HIV)和丙型肝炎病毒(HCV)合并感染患病率及其危险因素的原始研究,剖析南亚和东南亚地区HIV与HCV合并感染的流行病学意义。我们对PubMed数据库中2012年和2013年发表的13篇论文进行了综述。在南亚和东南亚地区,HIV阳性人群中HCV合并感染的总体患病率差异很大,从1.2%到98.5%不等。在尼泊尔HCV血清学阳性的献血者中,5.75%同时感染了HIV。注射吸毒是合并感染的关键危险因素之一,在越南,HIV阳性的注射吸毒者中HCV感染率分别达到89.8%和98.5%。来自南亚和东南亚地区的最新数据表明,实施HIV-HCV合并感染综合防控策略迫在眉睫。