Civil, Environmental and Sustainable Engineering, School of Sustainable Engineering and the Built Environment, Arizona State University, Tempe, AZ, 85287-5306, USA,
Adv Exp Med Biol. 2014;811:1-17. doi: 10.1007/978-94-017-8739-0_1.
Widespread use of engineered nanomaterials (ENMs) in consumer products has led to concerns about their potential impact on humans and the environment. In order to fully assess the impacts and release of ENMs from consumer products, this chapter provides an overview of the types of consumer products that contain nanomaterials, the potential release mechanisms of these ENMs from consumer products, and the associated human exposure. Information from two large datasets on consumer goods associated with ENMs, namely, the U.S.-based Project for Emerging Nanotechnologies from the Woodrow Wilson International Center, and the European-based National Institute for Public Health and the Environment of Netherlands, have been summarized. These databases reveal that silver, titanium, carbon-based ENMs are the major nanomaterials associated with consumer products. The presence and potential release of silver, titanium, carbon-based, and other nanomaterials from consumer goods available in published literature are also summarized, as well as the potential human exposure scenarios of inhalation, ingestion, dermal, and combination of all means. The prospecting of nanomaterial in water and biosolids provides further evidence of ENM occurrence, which could be linked to the use of nanomaterials containing consumer goods. Finally, this overview provides guidelines on toxicity studies, which calls for further efforts to analyze the biological effects of ENMs on human beings and their exposure pathways in consumer products.
工程纳米材料(ENMs)在消费品中的广泛应用引发了人们对其对人类和环境潜在影响的担忧。为了全面评估从消费品中释放的 ENMs 的影响,本章概述了含有纳米材料的消费品的类型、这些 ENMs 从消费品中释放的潜在机制以及相关的人体暴露情况。总结了来自美国伍德罗·威尔逊国际中心的新兴纳米技术项目和欧洲荷兰国家公共卫生和环境研究所这两个与 ENMs 相关的消费品大型数据集的信息。这些数据库显示,银、钛、基于碳的 ENMs 是与消费品相关的主要纳米材料。还总结了文献中报道的消费品中存在的和潜在释放的银、钛、基于碳的以及其他纳米材料,以及吸入、摄入、皮肤和所有这些途径的组合的潜在人体暴露情景。从水中和生物固体中寻找纳米材料进一步证明了 ENM 的存在,这可能与含有消费品的纳米材料的使用有关。最后,本概述提供了毒性研究的指导方针,呼吁进一步努力分析 ENMs 对人类的生物效应及其在消费品中的暴露途径。